Concepedia

Multi-modal Tissue Profiling

Multi-Modal Tissue Profiling is a spatial multi-omics methodology that integrates diverse molecular measurement modalities within intact tissue architectures to simultaneously capture complementary biological layers, such as genomics, transcriptomics, proteomics, and epigenomics, at spatially resolved resolutions.

8

Publications

644

Citations

120

Authors

68

Institutions

Publications per year

2017–2026

6

Parents

Publications

8

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues

Tongtong Zhao, Zachary Chiang, Julia W. Morriss et al. · Nature · 2021 · 270 citations · Full text

, , +14

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility

Frédéric Chalmel, Aurélie Lardenois, Bertrand Evrard et al. · Human Reproduction · 2012 · 119 citations · Full text

, , +14

A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project

Tarek M. El‐Achkar, Michael T. Eadon, Rajasree Menon et al. · Physiological Genomics · 2020 · 85 citations · Full text

, , +17

Resolving tissue complexity by multimodal spatial omics modeling with MISO

Kyle Coleman, Amelia Schroeder, Melanie Loth et al. · Nature Methods · 2025 · 60 citations · Full text

, , +14

In silico tissue generation and power analysis for spatial omics

Ethan A. G. Baker, Denis Schapiro, Bianca Dumitrascu et al. · Nature Methods · 2023 · 54 citations · Full text

, , +13

1–5 of 8

Authors

120

  1. DR
    Demetrio Raldúa

    Institute of Environmental Assessment and Water Research, Spain

    1 publications · 14 citations

    1

    h-index

  2. MK
    Min‐Ji Kim

    Samsung Medical Center, South Korea

    1 publications · 60 citations

    1

    h-index

  3. EA
    Edgar A. Otto

    University of Michigan, United States

    1 publications · 85 citations

    1

    h-index

  4. JS
    Ji‐Youn Sung

    Kyung Hee University, South Korea

    1 publications · 60 citations

    1

    h-index

  5. EE
    Emma E. Furth

    University of Pennsylvania, United States

    1 publications · 60 citations

    1

    h-index

1–5 of 120

Institutions

68

  1. Harvard University

    Cambridge, United States

    4 h-index

    11 publications

    2.4K citations

  2. The University of Texas Health Science Center at Houston

    Houston, United States

    2 h-index

    5 publications

    375 citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    6 publications

    1.2K citations

  4. Princeton University

    Princeton, United States

    2 h-index

    5 publications

    375 citations

  5. Broad Institute

    Cambridge, United States

    2 h-index

    17 publications

    3.5K citations

  6. University of Michigan

    Ann Arbor, United States

    2 h-index

    10 publications

    714 citations

  7. Beihang University

    Beijing, China

    1 h-index

    5 publications

    125 citations

  8. Ludwig Cancer Research

    New York, United States

    1 h-index

    2 publications

    120 citations

1–8 of 68

Venues

  1. Nature Methods

    2 publications · 114 citations

    2

    h-index

  2. Talanta

    1 publications · 14 citations

    1

    h-index

  3. Nature Communications

    1 publications · 25 citations

    1

    h-index

  4. Human Reproduction

    1 publications · 119 citations

    1

    h-index

  5. Nature

    1 publications · 270 citations

    1

    h-index

1–5