Concepedia

Mrna Cap-dependent Initiation

mRNA Cap-Dependent Initiation is a translation initiation mechanism in which the ribosome is recruited to the 5' cap structure of eukaryotic mRNA through the recognition and binding of initiation factors, distinguishing it from cap-independent initiation pathways that utilize internal ribosome entry sites.

183

Publications

16.7K

Citations

705

Authors

255

Institutions

Publications per year

2017–2026

16

Parents

Publications

183

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

M Kozak · Journal of Biological Chemistry · 1991 · 1.9K citations · Full text

, , +16

Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.

M Kozak · Proceedings of the National Academy of Sciences · 1986 · 710 citations · Full text

, , +17

Rapamycin blocks the phosphorylation of 4E‐BP1 and inhibits cap‐dependent initiation of translation.

Laura Beretta, Anne‐Claude Gingras, Yuri V. Svitkin et al. · The EMBO Journal · 1996 · 673 citations · Full text

, , +12

Repression of cap‐dependent translation by 4E‐binding protein 1: competition with p220 for binding to eukaryotic initiation factor‐4E.

Ashkan Haghighat, Sylvie Mader, Arnim Pause et al. · The EMBO Journal · 1995 · 610 citations · Full text

, , +15

Cap-Dependent Translation Initiation in Eukaryotes Is Regulated by a Molecular Mimic of eIF4G

Joseph Marcotrigiano, Anne‐Claude Gingras, Nahum Sonenberg et al. · Molecular Cell · 1999 · 512 citations · Full text

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1–5 of 183

Authors

705

  1. NS
    Nahum Sonenberg

    McGill University, Canada

    14 publications · 3.3K citations

    13

    h-index

  2. RE
    Robert E. Rhoads

    Louisiana State University Health Sciences Center Shreveport, United States

    8 publications · 608 citations

    8

    h-index

  3. WC
    William C. Merrick

    Case Western Reserve University, United States

    8 publications · 924 citations

    8

    h-index

  4. JP
    Jerry Pelletier

    McGill University, Canada

    6 publications · 518 citations

    6

    h-index

  5. YV
    Yuri V. Svitkin

    McGill University, Canada

    6 publications · 1.7K citations

    6

    h-index

1–5 of 705

Institutions

255

  1. McGill University

    Montreal, Canada

    18 h-index

    70 publications

    15K citations

  2. University of Warsaw

    Warsaw, Poland

    7 h-index

    36 publications

    1.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    29 publications

    2K citations

  4. Case Western Reserve University

    Cleveland, United States

    7 h-index

    12 publications

    1.1K citations

  5. Harvard University

    Cambridge, United States

    5 h-index

    19 publications

    1.7K citations

  6. University of Kansas Medical Center

    Kansas City, United States

    5 h-index

    22 publications

    804 citations

  7. Universidad Autónoma de Madrid

    Madrid, Spain

    5 h-index

    13 publications

    851 citations

  8. Scripps Research Institute

    San Diego, United States

    5 h-index

    14 publications

    444 citations

1–8 of 255

Venues

  1. Journal of Biological Chemistry

    JBC · 26 publications · 3.2K citations

    21

    h-index

  2. Nucleic Acids Research

    13 publications · 816 citations

    13

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 2K citations

    13

    h-index

  4. Molecular and Cellular Biology

    MCB · 7 publications · 1K citations

    7

    h-index

  5. Journal of Virology

    JVI · 7 publications · 287 citations

    7

    h-index

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