Concepedia

Mr-egger Regression

MR-Egger Regression is a statistical method in Mendelian randomization that extends instrumental variable analysis by allowing for directional pleiotropy through the inclusion of an intercept term in the regression model, thereby distinguishing it from conventional inverse-variance weighted approaches.

307

Publications

33K

Citations

1.7K

Authors

523

Institutions

Publications per year

2017–2026

302

Variants

Mr-egger

Parents

Publications

307

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Jack Bowden, George Davey Smith, Philip Haycock et al. · Genetic Epidemiology · 2016 · 9.6K citations · Full text

, , +12

Interpreting findings from Mendelian randomization using the MR-Egger method

Stephen Burgess, Simon G. Thompson · European Journal of Epidemiology · 2017 · 4.8K citations · Full text

, , +13

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

Fernando Pires Hartwig, George Davey Smith, Jack Bowden · International Journal of Epidemiology · 2017 · 3.7K citations · Full text

, , +16

A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization

Jack Bowden, Fabiola Del Greco M, Cosetta Minelli et al. · Statistics in Medicine · 2017 · 2K citations · Full text

, , +14

Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic

Jack Bowden, Fabiola Del Greco M, Cosetta Minelli et al. · International Journal of Epidemiology · 2016 · 1.7K citations · Full text

, , +13

1–5 of 307

Authors

1.7K

  1. YM
    Yingying Mao

    Zhejiang Chinese Medical University, China

    11 publications · 309 citations

    11

    h-index

  2. SB
    Stephen Burgess

    University of Cambridge, United Kingdom

    10 publications · 15.5K citations

    10

    h-index

  3. GD
    George Davey Smith

    University of Bristol, United Kingdom

    9 publications · 17.2K citations

    9

    h-index

  4. JB
    Jack Bowden

    University of Bristol, United Kingdom

    9 publications · 17.6K citations

    9

    h-index

  5. XS
    Xiaohui Sun

    Zhejiang Chinese Medical University, China

    6 publications · 188 citations

    6

    h-index

1–5 of 1.7K

Institutions

523

  1. Central South University

    Changsha, China

    18 h-index

    92 publications

    4.6K citations

  2. Zhejiang Chinese Medical University

    Hangzhou, China

    15 h-index

    113 publications

    2.9K citations

  3. University of Bristol

    Bristol, United Kingdom

    14 h-index

    47 publications

    45.6K citations

  4. Sun Yat-sen University

    Guangzhou, China

    14 h-index

    80 publications

    3.5K citations

  5. Zhejiang University

    Hangzhou, China

    13 h-index

    47 publications

    1.1K citations

  6. Karolinska Institutet

    Stockholm, Sweden

    12 h-index

    33 publications

    1.9K citations

  7. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    11 h-index

    38 publications

    648 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    11 h-index

    25 publications

    22.1K citations

1–8 of 523

Venues

  1. Frontiers in Endocrinology

    23 publications · 640 citations

    18

    h-index

  2. Frontiers in Genetics

    25 publications · 616 citations

    17

    h-index

  3. Frontiers in Immunology

    19 publications · 698 citations

    16

    h-index

  4. Scientific Reports

    12 publications · 243 citations

    11

    h-index

  5. Frontiers in Microbiology

    10 publications · 326 citations

    10

    h-index

1–5