Concepedia

Morphogen Gradient Response

Morphogen Gradient Response is a biological mechanism in stem cell differentiation whereby cells interpret spatial variations in morphogen concentration to activate specific gene expression programs that determine cell fate in a dose-dependent manner.

36

Publications

3.1K

Citations

148

Authors

76

Institutions

Publications per year

2017–2026

7

Parents

Publications

36

Wingless Repression of Drosophila frizzled 2 Expression Shapes the Wingless Morphogen Gradient in the Wing

Ken M. Cadigan, Matthew Fish, Eric Rulifson et al. · Cell · 1998 · 331 citations · Full text

, , +17

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

Jie Jiang · Cell · 1993 · 328 citations · Full text

, , +16

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

Marcus Bischoff, Ana‐Citlali Gradilla, Irene Seijo-Barandiarán et al. · Nature Cell Biology · 2013 · 258 citations · Full text

, , +14

HSPG Modification by the Secreted Enzyme Notum Shapes the Wingless Morphogen Gradient

Antonio J. Giráldez, Richard R. Copley, Stephen M. Cohen · Developmental Cell · 2002 · 246 citations · Full text

, , +16

Regulation of Cell Proliferation by a Morphogen Gradient

Dragana Rogulja, Kenneth D. Irvine · Cell · 2005 · 210 citations · Full text

, , +14

1–5 of 36

Authors

148

  1. JC
    James C. Smith

    University of Cambridge, United Kingdom

    4 publications · 285 citations

    4

    h-index

  2. JB
    J. B. Gurdon

    University of Cambridge, United Kingdom

    2 publications · 165 citations

    2

    h-index

  3. SP
    Spyros Papageorgiou

    National Centre of Scientific Research "Demokritos", Greece

    2 publications · 54 citations

    2

    h-index

  4. JM
    Jun Ma

    Cincinnati Children's Hospital Medical Center, United States

    2 publications · 117 citations

    2

    h-index

  5. KS
    Kazuya Shimizu

    University of Tsukuba, Japan

    2 publications · 165 citations

    2

    h-index

1–5 of 148

Institutions

76

  1. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    17 publications

    1.4K citations

  2. The Gurdon Institute

    Cambridge, United Kingdom

    4 h-index

    10 publications

    548 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    13 publications

    2K citations

  4. Inserm

    Paris, France

    3 h-index

    9 publications

    109 citations

  5. Harvard University

    Cambridge, United States

    3 h-index

    9 publications

    976 citations

  6. Wellcome Trust

    London, United Kingdom

    3 h-index

    6 publications

    370 citations

  7. Center for Systems Biology

    Boston, United States

    2 h-index

    2 publications

    135 citations

  8. Harvard Stem Cell Institute

    Cambridge, United States

    2 h-index

    3 publications

    151 citations

1–8 of 76

Venues

  1. Cell

    4 publications · 1K citations

    4

    h-index

  2. Developmental Cell

    3 publications · 443 citations

    3

    h-index

  3. Developmental Biology

    3 publications · 316 citations

    3

    h-index

  4. Development

    3 publications · 107 citations

    3

    h-index

  5. eLife

    2 publications · 132 citations

    2

    h-index

1–5