Molecular Clock Hypothesis Testing is a statistical framework used in molecular evolution to assess the validity of the assumption that nucleotide or amino acid substitution rates are constant over time by comparing observed genetic distances with those predicted under a clock-like model of divergence.
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Simple methods for testing the molecular evolutionary clock hypothesis.
Fumio Tajima · Genetics · 1993 · 963 citations · Full text
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University of Southern California
Los Angeles, United States
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Sanford Burnham Prebys Medical Discovery Institute
La Jolla, United States
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Pennsylvania State University
State College, United States
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University of Ottawa
Ottawa, Canada
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The Graduate University for Advanced Studies, SOKENDAI
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University of California, Irvine
Irvine, United States
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German Centre for Integrative Biodiversity Research
Leipzig, Germany
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Robert Koch Institute
Berlin, Germany
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- Evolution
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