Concepedia

Modifier Gene Identification

Modifier Gene Identification is the systematic discovery of genetic loci that alter the phenotypic expression of a primary mutation, thereby revealing epistatic relationships and functional interactions within a genetic network.

99

Publications

5.8K

Citations

755

Authors

311

Institutions

Publications per year

2017–2026

18

Parents

Publications

99

Digenic Inheritance of Early-Onset Glaucoma: CYP1B1, a Potential Modifier Gene

Andrea L. Vincent, Gail Billingsley, Yvonne M. Buys et al. · The American Journal of Human Genetics · 2002 · 308 citations · Full text

, , +12

A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.

G Lombard-Platet, Stéphane Savary, Claude‐Olivier Sarde et al. · Proceedings of the National Academy of Sciences · 1996 · 226 citations

, , +13

Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

Taye H. Hamza, Honglei Chen, Erin M. Hill‐Burns et al. · PLoS Genetics · 2011 · 224 citations · Full text

, , +17

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

Marzena Maka, C. Claus Stolt, Michael Wegner · Developmental Biology · 2004 · 167 citations

, , +8

A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene

Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood et al. · Nature · 2019 · 166 citations

, , +13

1–5 of 99

Authors

755

  1. MW
    Michael Wegner

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    3 publications · 277 citations

    3

    h-index

  2. YB
    Yelena Bykhovskaya

    Cedars-Sinai Medical Center, United States

    3 publications · 233 citations

    3

    h-index

  3. MG
    Min‐Xin Guan

    Cincinnati Children's Hospital Medical Center, United States

    3 publications · 276 citations

    3

    h-index

  4. HC
    Harriet Corvol

    Sorbonne Université, France

    3 publications · 165 citations

    3

    h-index

  5. GR
    Garry R. Cutting

    Johns Hopkins University, United States

    3 publications · 273 citations

    3

    h-index

1–5 of 755

Institutions

311

  1. Inserm

    Paris, France

    9 h-index

    67 publications

    5.1K citations

  2. National Institutes of Health

    Bethesda, United States

    5 h-index

    15 publications

    785 citations

  3. University of Cincinnati Medical Center

    Cincinnati, United States

    5 h-index

    8 publications

    902 citations

  4. Assistance Publique – Hôpitaux de Paris

    Paris, France

    5 h-index

    24 publications

    2.4K citations

  5. Johns Hopkins University

    Baltimore, United States

    5 h-index

    15 publications

    885 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    15 publications

    534 citations

  7. Case Western Reserve University

    Cleveland, United States

    4 h-index

    7 publications

    514 citations

  8. University of Toronto

    Toronto, Canada

    4 h-index

    19 publications

    2.8K citations

1–8 of 311

Venues

  1. PubMed

    Repository · 6 publications · 248 citations

    6

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 529 citations

    6

    h-index

  3. Genetics

    3 publications · 140 citations

    3

    h-index

  4. Blood

    3 publications · 284 citations

    3

    h-index

  5. The American Journal of Human Genetics

    AJHG · 3 publications · 537 citations

    3

    h-index

1–5