Concepedia

Model-based Precision Dosing

Model-Based Precision Dosing is a pharmacometric approach that uses mathematical models of drug pharmacokinetics and pharmacodynamics, integrated with individual patient characteristics, to optimize drug dosage regimens by predicting the most effective and safe dose for a specific patient.

56

Publications

2.1K

Citations

320

Authors

176

Institutions

Publications per year

2017–2026

56

Parents

Publications

56

Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting

Astrid Broeker, Marco Nardecchia, Kenneth Klinker et al. · Clinical Microbiology and Infection · 2019 · 136 citations · Full text

, , +17

Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities

Ron J. Keizer, Rob ter Heine, Adam Frymoyer et al. · CPT Pharmacometrics & Systems Pharmacology · 2018 · 119 citations · Full text

, , +14

Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs?

Wannee Kantasiripitak, Ruth Van Daele, Matthias Gijsen et al. · Frontiers in Pharmacology · 2020 · 115 citations · Full text

, , +13

Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial

Tim M. J. Ewoldt, Alan Abdulla, Wim J. R. Rietdijk et al. · Intensive Care Medicine · 2022 · 111 citations · Full text

, , +17

Developmental pharmacokinetics of sirolimus: Implications for precision dosing in neonates and infants with complicated vascular anomalies

Tomoyuki Mizuno, Tsuyoshi Fukuda, Chie Emoto et al. · Pediatric Blood & Cancer · 2017 · 86 citations

, , +17

1–5 of 56

Authors

320

  1. SG
    Sebastian G. Wicha

    Universität Hamburg, Germany

    8 publications · 403 citations

    8

    h-index

  2. AA
    Alexander A. Vinks

    Cincinnati Children's Hospital Medical Center, United States

    6 publications · 278 citations

    6

    h-index

  3. RJ
    Ron J. Keizer

    Slotervaartziekenhuis, Netherlands

    6 publications · 331 citations

    6

    h-index

  4. TM
    Thomas M. Polasek

    Flinders University, Australia

    5 publications · 166 citations

    5

    h-index

  5. AR
    Amin Rostami‐Hodjegan

    University of Manchester, United Kingdom

    5 publications · 183 citations

    5

    h-index

1–5 of 320

Institutions

176

  1. Universität Hamburg

    Hamburg, Germany

    8 h-index

    18 publications

    1K citations

  2. Cincinnati Children's Hospital Medical Center

    Cincinnati, United States

    6 h-index

    46 publications

    2.1K citations

  3. University of Manchester

    Manchester, United Kingdom

    5 h-index

    8 publications

    292 citations

  4. University of Cincinnati Medical Center

    Cincinnati, United States

    5 h-index

    24 publications

    1.1K citations

  5. Certara (United States)

    St Louis, United States

    5 h-index

    10 publications

    365 citations

  6. Integra LifeSciences (United States)

    Plainsboro Center, United States

    5 h-index

    10 publications

    365 citations

  7. Radboud University Nijmegen

    Nijmegen, The Netherlands

    4 h-index

    11 publications

    570 citations

  8. Monash University

    Melbourne, Australia

    4 h-index

    7 publications

    219 citations

1–8 of 176

Venues

  1. Frontiers in Pharmacology

    11 publications · 418 citations

    11

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 7 publications · 350 citations

    7

    h-index

  3. CPT Pharmacometrics & Systems Pharmacology

    PSP · 7 publications · 283 citations

    7

    h-index

  4. Clinical Pharmacokinetics

    3 publications · 76 citations

    3

    h-index

  5. Antimicrobial Agents and Chemotherapy

    AAC · 2 publications · 34 citations

    2

    h-index

1–5