Concepedia

Mitochondrial Base Editing

Mitochondrial Base Editing is a genome editing technique that enables precise, programmable modification of mitochondrial DNA through the targeted deamination of nucleotide bases without inducing double-strand breaks.

38

Publications

3.2K

Citations

211

Authors

94

Institutions

Publications per year

2017–2026

31

Parents

Publications

38

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing

Beverly Mok, Marcos H. de Moraes, Jun Zeng et al. · Nature · 2020 · 721 citations · Full text

, , +11

Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases

Sung-Ik Cho, Seonghyun Lee, Young Geun Mok et al. · Cell · 2022 · 250 citations

, , +13

CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA

Beverly Mok, Anna V. Kotrys, Aditya Raguram et al. · Nature Biotechnology · 2022 · 207 citations · Full text

, , +16

Chloroplast and mitochondrial DNA editing in plants

Beum‐Chang Kang, Su‐Ji Bae, Seonghyun Lee et al. · Nature Plants · 2021 · 190 citations · Full text

, , +17

Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism

Rodolphe Suspène, Marie-Ming Aynaud, Denise Guétard et al. · Proceedings of the National Academy of Sciences · 2011 · 168 citations · Full text

, , +14

1–5 of 38

Authors

211

  1. JK
    Jin‐Soo Kim

    Seoul National University, South Korea

    9 publications · 1.1K citations

    7

    h-index

  2. SC
    Sung-Ik Cho

    Institute for Basic Science, South Korea

    5 publications · 535 citations

    5

    h-index

  3. BS
    Bin Shen

    Nanjing Medical University, China

    3 publications · 190 citations

    4

    h-index

  4. DR
    David R. Liu

    Harvard University, United States

    3 publications · 994 citations

    4

    h-index

  5. KL
    Kayeong Lim

    Institute for Basic Science, South Korea

    4 publications · 466 citations

    4

    h-index

1–5 of 211

Institutions

94

  1. Institute for Basic Science

    Daejeon, South Korea

    7 h-index

    45 publications

    5.9K citations

  2. Seoul National University

    Seoul, South Korea

    6 h-index

    14 publications

    1.8K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    18 publications

    5.8K citations

  4. Nanjing Medical University

    Nanjing, China

    4 h-index

    32 publications

    2K citations

  5. Harvard University

    Cambridge, United States

    4 h-index

    13 publications

    4.8K citations

  6. Nanjing Maternity and Child Health Care Hospital

    Nanjing, China

    4 h-index

    14 publications

    524 citations

  7. Broad Institute

    Cambridge, United States

    4 h-index

    14 publications

    5K citations

  8. Center for Life Sciences

    Beijing, China

    3 h-index

    16 publications

    1.6K citations

1–8 of 94

Venues

  1. Nature Communications

    6 publications · 387 citations

    6

    h-index

  2. Nature Biotechnology

    3 publications · 407 citations

    3

    h-index

  3. Nature Plants

    3 publications · 391 citations

    3

    h-index

  4. Molecular Therapy — Nucleic Acids

    1 publications · 74 citations

    2

    h-index

  5. Cell

    2 publications · 321 citations

    2

    h-index

1–5