Concepedia

Misincorporation Suppression

Misincorporation Suppression is a translational fidelity mechanism that selectively prevents the erroneous incorporation of non-cognate amino acids during protein synthesis by enhancing the accuracy of aminoacyl-tRNA selection at the ribosomal A-site.

37

Publications

2.1K

Citations

156

Authors

65

Institutions

Publications per year

2017–2026

3

Parents

Publications

37

Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells

Josef Jiricny · Cell · 1988 · 229 citations

, , +4

MSH2 and MSH6 Are Required for Removal of Adenine Misincorporated Opposite 8-Oxo-Guanine in S. cerevisiae

Terri T. Ni, Gerald Marsischky, Richard D. Kolodner · Molecular Cell · 1999 · 226 citations · Full text

, , +5

A temperature-sensitive mutant of Escherichia coli that shows enhanced misreading of UAG/A and increased efficiency for tRNA nonsense suppressors

S. M. Rydén, Leif A. Isaksson · Molecular and General Genetics MGG · 1984 · 130 citations

, , +9

Misincorporation by Wild-Type and Mutant T7 RNA Polymerases:  Identification of Interactions That Reduce Misincorporation Rates by Stabilizing the Catalytically Incompetent Open Conformation

Jianbin Huang, Luis G. Brieba, Rui Sousa · Biochemistry · 2000 · 121 citations

, , +10

Identification of amino acids inserted during suppression of UAA and UGA termination codons at the gag-pol junction of Moloney murine leukemia virus.

Yan Feng, T D Copeland, S Oroszlan et al. · Proceedings of the National Academy of Sciences · 1990 · 82 citations

, , +16

1–5 of 37

Authors

156

  1. PM
    Peter M. Kilby

    Syngenta (United Kingdom), United Kingdom

    2 publications · 47 citations

    2

    h-index

  2. RH
    Robert Harris

    Syngenta (United Kingdom), United Kingdom

    2 publications · 47 citations

    2

    h-index

  3. MF
    Myron F. Goodman

    University of Southern California, United States

    1 publications · 73 citations

    1

    h-index

  4. RN
    Rebecca N. Williams-Wagner

    The Ohio State University, United States

    1 publications · 26 citations

    1

    h-index

  5. JS
    John Stewart

    University of Saskatchewan, Canada

    1 publications · 18 citations

    1

    h-index

1–5 of 156

Institutions

65

  1. National Institutes of Health

    Bethesda, United States

    3 h-index

    13 publications

    999 citations

  2. Syngenta (United Kingdom)

    Fulbourn, United Kingdom

    2 h-index

    6 publications

    107 citations

  3. Harvard University

    Cambridge, United States

    2 h-index

    7 publications

    201 citations

  4. Johns Hopkins University

    Baltimore, United States

    2 h-index

    6 publications

    204 citations

  5. UPMC Hillman Cancer Center

    Pittsburgh, United States

    2 h-index

    4 publications

    270 citations

  6. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    1 h-index

    3 publications

    363 citations

  7. University of Southern California

    Los Angeles, United States

    1 h-index

    2 publications

    146 citations

  8. National Cancer Institute

    Bethesda, United States

    1 h-index

    1 publications

    22 citations

1–8 of 65

Venues

  1. Nucleic Acids Research

    4 publications · 122 citations

    4

    h-index

  2. BioTechniques

    3 publications · 204 citations

    3

    h-index

  3. Biochemistry

    3 publications · 147 citations

    3

    h-index

  4. Cell

    2 publications · 310 citations

    2

    h-index

  5. Molecular and General Genetics MGG

    2 publications · 144 citations

    2

    h-index

1–5