Concepedia

Microtubule Mutation

Microtubule Mutation is a genetic alteration affecting the structural protein components of microtubules, specifically distinguished from other target-site mutations by its direct impact on tubulin subunits that disrupts microtubule dynamics and function.

68

Publications

4K

Citations

422

Authors

187

Institutions

Publications per year

2017–2026

16

Parents

Publications

68

Paclitaxel Resistance in Non–Small-Cell Lung Cancer Associated With Beta-Tubulin Gene Mutations

Mariano Monzó, Rafael Rosell, José Javier Sánchez et al. · Journal of Clinical Oncology · 1999 · 315 citations

, , +17

A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum

Cas Simons, Nicole I. Wolf, Nathan McNeil et al. · The American Journal of Human Genetics · 2013 · 194 citations · Full text

, , +16

A β-tubulin mutation in Aspergillus nidulans that blocks microtubule function without blocking assembly

Berl R. Oakley, N. Ronald Morris · Cell · 1981 · 180 citations

, , +16

Mutation of the β1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly

Shinji Kunishima, Ryōji Kobayashi, Tomohiko J. Itoh et al. · Blood · 2008 · 179 citations · Full text

, , +13

Mutation of the Variant α-Tubulin TUBA8 Results in Polymicrogyria with Optic Nerve Hypoplasia

Mohammad Reza Abdollahi, Ewan E. Morrison, Tamara Sirey et al. · The American Journal of Human Genetics · 2009 · 167 citations · Full text

, , +11

1–5 of 68

Authors

422

  1. BR
    Berl R. Oakley

    The Ohio State University, United States

    5 publications · 437 citations

    5

    h-index

  2. JK
    Jeffrey K. Moore

    University of Colorado Denver, United States

    4 publications · 120 citations

    4

    h-index

  3. CE
    C. Elizabeth Oakley

    The Ohio State University, United States

    3 publications · 128 citations

    3

    h-index

  4. MC
    Martin Chalfie

    Columbia University, United States

    2 publications · 41 citations

    2

    h-index

  5. TH
    Takashi Hashimoto

    Nara Institute of Science and Technology, Japan

    2 publications · 110 citations

    2

    h-index

1–5 of 422

Institutions

187

  1. University of Colorado Denver

    Denver, United States

    4 h-index

    12 publications

    360 citations

  2. Assistance Publique – Hôpitaux de Paris

    Paris, France

    3 h-index

    8 publications

    249 citations

  3. University of Michigan

    Ann Arbor, United States

    3 h-index

    9 publications

    276 citations

  4. The Ohio State University

    Columbus, United States

    3 h-index

    10 publications

    405 citations

  5. University of California, Berkeley

    Berkeley, United States

    3 h-index

    6 publications

    438 citations

  6. Institut Cochin

    Paris, France

    2 h-index

    7 publications

    230 citations

  7. Nara Institute of Science and Technology

    Ikoma, Japan

    2 h-index

    5 publications

    312 citations

  8. Nagoya Medical Center

    Nagoya, Japan

    2 h-index

    4 publications

    516 citations

1–8 of 187

Venues

  1. Cancer Letters

    3 publications · 92 citations

    3

    h-index

  2. Genetics

    3 publications · 116 citations

    3

    h-index

  3. European Journal of Medical Genetics

    2 publications · 45 citations

    2

    h-index

  4. Developmental Biology

    2 publications · 74 citations

    2

    h-index

  5. Plant and Cell Physiology

    PCP · 2 publications · 112 citations

    2

    h-index

1–5