Concepedia

Microglial Complement Signaling

Microglial Complement Signaling is a molecular communication mechanism within the neuroimmune system wherein microglia detect and respond to complement proteins through specific receptors, thereby mediating synaptic pruning, neuroinflammation, and CNS homeostasis.

37

Publications

8K

Citations

234

Authors

104

Institutions

Publications per year

2017–2026

23

Parents

Publications

37

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Dorothy P. Schafer, Emily K. Lehrman, Amanda G. Kautzman et al. · Neuron · 2012 · 4.1K citations · Full text

, , +14

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Hansen Lui, Jiasheng Zhang, Stefanie Ritter Makinson et al. · Cell · 2016 · 736 citations · Full text

, , +12

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

Hong Lian, Alexandra Litvinchuk, Angie C.A. Chiang et al. · Journal of Neuroscience · 2016 · 600 citations · Full text

, , +17

Increased Complement Biosynthesis By Microglia and Complement Activation on Neurons in Huntington's Disease

Sim K. Singhrao, James Neal, B. Paul Morgan et al. · Experimental Neurology · 1999 · 315 citations

, , +14

Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats

Ashley M. Kopec, Caroline J. Smith, Nathan R. Ayre et al. · Nature Communications · 2018 · 265 citations · Full text

, , +17

1–5 of 37

Authors

234

  1. BA
    Ben A. Barres

    Stanford University, United States

    3 publications · 4.9K citations

    3

    h-index

  2. TY
    Ted Yednock

    Sunesis (United States), United States

    1 publications · 125 citations

    2

    h-index

  3. AG
    Amanda G. Kautzman

    University of Massachusetts Chan Medical School, United States

    2 publications · 4.2K citations

    2

    h-index

  4. KI
    Kazuhiko Ikeda

    Tokyo Institute of Psychiatry, Japan

    2 publications · 190 citations

    2

    h-index

  5. LY
    Li‐Tao Yi

    Huaqiao University, China

    2 publications · 95 citations

    2

    h-index

1–5 of 234

Institutions

104

  1. Harvard University

    Cambridge, United States

    5 h-index

    20 publications

    32.4K citations

  2. Stanford University

    Stanford, United States

    3 h-index

    4 publications

    5.7K citations

  3. Montreal Neurological Institute and Hospital

    Montreal, Canada

    2 h-index

    2 publications

    250 citations

  4. Jiangxi University of Traditional Chinese Medicine

    Nanchang, China

    2 h-index

    4 publications

    257 citations

  5. Zhongda Hospital Southeast University

    Nanjing, China

    2 h-index

    13 publications

    430 citations

  6. Massachusetts General Hospital

    Boston, United States

    2 h-index

    11 publications

    2.8K citations

  7. McGill University

    Montreal, Canada

    2 h-index

    2 publications

    250 citations

  8. University College London

    London, United Kingdom

    2 h-index

    4 publications

    494 citations

1–8 of 104

Venues

  1. Brain Research

    3 publications · 214 citations

    3

    h-index

  2. Journal of Neuroscience

    3 publications · 956 citations

    3

    h-index

  3. Journal of Neuroinflammation

    JNI · 2 publications · 110 citations

    2

    h-index

  4. Experimental Neurology

    1 publications · 315 citations

    2

    h-index

  5. Nature Communications

    1 publications · 265 citations

    2

    h-index

1–5