Concepedia

Microglia-mediated Synaptic Remodeling

Microglia-Mediated Synaptic Remodeling is a biological process in which microglial cells selectively eliminate or modify synaptic connections in the developing or diseased nervous system through phagocytic activity and signaling interactions, thereby shaping neural circuit architecture.

115

Publications

16.3K

Citations

816

Authors

291

Institutions

Publications per year

2017–2026

81

Parents

Publications

115

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

Christopher N. Parkhurst, Guang Yang, Ipe Ninan et al. · Cell · 2013 · 2.6K citations · Full text

, , +14

Microglial Interactions with Synapses Are Modulated by Visual Experience

Marie‐Ève Tremblay, Rebecca L. Lowery, Ania K. Majewska · PLoS Biology · 2010 · 1.6K citations · Full text

, , +17

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

Laetitia Weinhard, Giulia Di Bartolomei, Giulia Bolasco et al. · Nature Communications · 2018 · 801 citations · Full text

, , +17

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

Phi T. Nguyen, Leah C. Dorman, Simon Pan et al. · Cell · 2020 · 622 citations · Full text

, , +14

Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects

HJ Kim, M-H Cho, Won Heum Shim et al. · Molecular Psychiatry · 2016 · 493 citations · Full text

, , +17

1–5 of 115

Authors

816

  1. MT
    Marie‐Ève Tremblay

    Université Laval, Canada

    10 publications · 2.2K citations

    10

    h-index

  2. BS
    Beth Stevens

    Boston Children's Hospital, United States

    5 publications · 712 citations

    5

    h-index

  3. ES
    Eric S. Wohleb

    University of Cincinnati Medical Center, United States

    5 publications · 593 citations

    5

    h-index

  4. FF
    Fabia Filipello

    Humanitas University, Italy

    5 publications · 650 citations

    5

    h-index

  5. AK
    Ania K. Majewska

    University of Rochester, United States

    5 publications · 1.9K citations

    5

    h-index

1–5 of 816

Institutions

291

  1. Université Laval

    Québec, Canada

    8 h-index

    15 publications

    979 citations

  2. Harvard University

    Cambridge, United States

    7 h-index

    25 publications

    2.1K citations

  3. University of Cincinnati Medical Center

    Cincinnati, United States

    6 h-index

    16 publications

    1.2K citations

  4. Boston Children's Hospital

    Boston, United States

    6 h-index

    22 publications

    3.2K citations

  5. University of Rochester

    Rochester, United States

    6 h-index

    21 publications

    5.7K citations

  6. Humanitas University

    Rozzano, Italy

    6 h-index

    30 publications

    5.5K citations

  7. University of California, Irvine

    Irvine, United States

    5 h-index

    32 publications

    7.2K citations

  8. IRCCS Humanitas Research Hospital

    Rozzano, Italy

    5 h-index

    35 publications

    5.4K citations

1–8 of 291

Venues

  1. Brain Behavior and Immunity

    8 publications · 830 citations

    8

    h-index

  2. Journal of Neuroinflammation

    JNI · 5 publications · 196 citations

    5

    h-index

  3. Glia

    6 publications · 361 citations

    5

    h-index

  4. Molecular Psychiatry

    4 publications · 845 citations

    4

    h-index

  5. Cell Reports

    4 publications · 229 citations

    4

    h-index

1–5