Concepedia

Microglia-mediated Synaptic Plasticity

Microglia-Mediated Synaptic Plasticity is a biological mechanism by which microglial cells actively regulate synaptic strength, connectivity, and neural circuit remodeling through contact-dependent signaling, phagocytic pruning of synapses, and release of neuroactive molecules, thereby distinguishing it from other forms of synaptic plasticity that are primarily neuron-autonomous.

125

Publications

12.6K

Citations

878

Authors

293

Institutions

Publications per year

2017–2026

86

Parents

Publications

125

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

Christopher N. Parkhurst, Guang Yang, Ipe Ninan et al. · Cell · 2013 · 2.6K citations · Full text

, , +14

Resting Microglia Directly Monitor the Functional State of Synapses<i>In Vivo</i>and Determine the Fate of Ischemic Terminals

Hiroaki Wake, Andrew J. Moorhouse, Shozo Jinno et al. · Journal of Neuroscience · 2009 · 1.6K citations · Full text

, , +16

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

Phi T. Nguyen, Leah C. Dorman, Simon Pan et al. · Cell · 2020 · 622 citations · Full text

, , +14

Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex

Rianne Stowell, Grayson O. Sipe, Ryan P. Dawes et al. · Nature Neuroscience · 2019 · 333 citations · Full text

, , +16

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism

Flavia Antonucci, Elena Turola, Loredana Riganti et al. · The EMBO Journal · 2012 · 325 citations · Full text

, , +14

1–5 of 125

Authors

878

  1. AK
    Ania K. Majewska

    University of Rochester, United States

    7 publications · 699 citations

    7

    h-index

  2. MT
    Marie‐Ève Tremblay

    Université Laval, Canada

    6 publications · 513 citations

    6

    h-index

  3. LM
    Laura Maggi

    Sapienza University of Rome, Italy

    4 publications · 260 citations

    4

    h-index

  4. DR
    Davide Ragozzino

    Sapienza University of Rome, Italy

    4 publications · 252 citations

    4

    h-index

  5. SG
    Stefano Garofalo

    Sapienza University of Rome, Italy

    3 publications · 229 citations

    3

    h-index

1–5 of 878

Institutions

293

  1. Sapienza University of Rome

    Rome, Italy

    8 h-index

    41 publications

    3.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    19 publications

    858 citations

  3. Fondazione Santa Lucia

    Rome, Italy

    6 h-index

    37 publications

    2.5K citations

  4. University of Rochester

    Rochester, United States

    5 h-index

    15 publications

    1.2K citations

  5. Université Laval

    Québec, Canada

    5 h-index

    9 publications

    668 citations

  6. German Center for Neurodegenerative Diseases

    Bonn, Germany

    4 h-index

    16 publications

    862 citations

  7. Nanjing University

    Nanjing, China

    4 h-index

    5 publications

    146 citations

  8. Institute of Cell Biology and Neurobiology

    Monterotondo, Italy

    4 h-index

    9 publications

    669 citations

1–8 of 293

Venues

  1. Brain Behavior and Immunity

    11 publications · 867 citations

    11

    h-index

  2. Frontiers in Cellular Neuroscience

    8 publications · 437 citations

    8

    h-index

  3. Journal of Neuroscience

    8 publications · 2.3K citations

    8

    h-index

  4. Glia

    7 publications · 448 citations

    6

    h-index

  5. Cell Reports

    5 publications · 376 citations

    5

    h-index

1–5