Concepedia

Metabolite Sensing

Metabolite Sensing is a regulatory mechanism in microbial systems that detects intracellular concentrations of specific metabolic intermediates or end products to modulate gene expression and enzyme activity in response to nutrient availability, thereby integrating catabolite repression and maintaining microbial homeostasis.

100

Publications

9K

Citations

612

Authors

240

Institutions

Publications per year

2017–2026

52

Parents

Publications

100

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

Laurence Macia, Jian Tan, Angélica T. Vieira et al. · Nature Communications · 2015 · 1.4K citations · Full text

, , +17

Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in <i>Saccharomyces cerevisiae</i>

Per O. Ljungdahl, Bertrand Daignan‐Fornier · Genetics · 2012 · 542 citations · Full text

, , +15

Acute Metformin Therapy Confers Cardioprotection Against Myocardial Infarction Via AMPK-eNOS–Mediated Signaling

John W. Calvert, Susheel Gundewar, Saurabh Kumar Jha et al. · Diabetes · 2007 · 421 citations · Full text

, , +13

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

David M. Kaye, Waled Shihata, Hamdi Jama et al. · Circulation · 2020 · 403 citations · Full text

, , +17

Riboswitch Control of Gene Expression in Plants by Splicing and Alternative 3′ End Processing of mRNAs

Andreas Wachter, Meral Tunc‐Ozdemir, Beth C. Grove et al. · The Plant Cell · 2007 · 338 citations · Full text

, , +17

1–5 of 100

Authors

612

  1. CR
    Charles R. Mackay

    Monash University, Australia

    4 publications · 2.1K citations

    4

    h-index

  2. MH
    Matthias Heinemann

    University of Groningen, Netherlands

    3 publications · 513 citations

    3

    h-index

  3. RM
    Róisı́n M. Owens

    University of Cambridge, United Kingdom

    3 publications · 427 citations

    3

    h-index

  4. RR
    Ronald R. Breaker

    Yale University, United States

    3 publications · 418 citations

    3

    h-index

  5. SR
    Samie R. Jaffrey

    Cornell University, United States

    3 publications · 397 citations

    3

    h-index

1–5 of 612

Institutions

240

  1. University of Chinese Academy of Sciences

    Beijing, China

    5 h-index

    14 publications

    409 citations

  2. Yale University

    New Haven, United States

    5 h-index

    14 publications

    3.4K citations

  3. Monash University

    Melbourne, Australia

    5 h-index

    37 publications

    22.2K citations

  4. Chinese Academy of Sciences

    Beijing, China

    5 h-index

    33 publications

    1K citations

  5. Cornell University

    Ithaca, United States

    4 h-index

    10 publications

    1.2K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    6 publications

    1.9K citations

  7. Harvard University

    Cambridge, United States

    4 h-index

    15 publications

    1.7K citations

  8. Imperial College London

    London, United Kingdom

    3 h-index

    5 publications

    879 citations

1–8 of 240

Venues

  1. ACS Synthetic Biology

    6 publications · 312 citations

    6

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 786 citations

    6

    h-index

  3. Nature Communications

    5 publications · 1.8K citations

    5

    h-index

  4. Biosensors and Bioelectronics

    5 publications · 160 citations

    5

    h-index

  5. Nucleic Acids Research

    4 publications · 215 citations

    4

    h-index

1–5