Concepedia

Metabolic Burden Optimization

Metabolic Burden Optimization is a computational and experimental methodology in synthetic biology that systematically minimizes the energetic and resource-based constraints imposed by heterologous gene expression on host cellular processes to enhance the performance and stability of whole-cell biosensors.

28

Publications

2.1K

Citations

146

Authors

56

Institutions

Publications per year

2017–2026

15

Parents

Publications

28

Plasmid‐encoded protein: The principal factor in the “metabolic burden” associated with recombinant bacteria

William E. Bentley, N. Mirjalili, Dana C. Andersen et al. · Biotechnology and Bioengineering · 1990 · 538 citations

, , +16

Complete Biosynthesis of Anthocyanins Using <i>E. coli</i> Polycultures

J. Andrew Jones, Victoria R. Vernacchio, Shannon M. Collins et al. · mBio · 2017 · 199 citations · Full text

, , +17

Impact of the Expression System on Recombinant Protein Production in Escherichia coli BL21

Gema Lozano Terol, Julia Gallego‐Jara, Rosa Alba Sola Martínez et al. · Frontiers in Microbiology · 2021 · 129 citations · Full text

, , +17

Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures

Joel Jordà, Paula Jouhten, Elena Cámara et al. · Microbial Cell Factories · 2012 · 127 citations · Full text

, , +17

A bet-hedging strategy for denitrifying bacteria curtails their release of N <sub>2</sub> O

Pawel Lycus, Manuel J. Soriano‐Laguna, Morten Kjos et al. · Proceedings of the National Academy of Sciences · 2018 · 117 citations · Full text

, , +17

1–5 of 28

Authors

146

  1. DS
    Dhinakar S. Kompala

    University of Colorado Boulder, United States

    3 publications · 681 citations

    3

    h-index

  2. WE
    William E. Bentley

    University of Maryland, College Park, United States

    2 publications · 635 citations

    2

    h-index

  3. DC
    Dana C. Andersen

    University of Alberta, Canada

    2 publications · 635 citations

    2

    h-index

  4. NM
    N. Mirjalili

    University College London, United Kingdom

    2 publications · 635 citations

    2

    h-index

  5. KB
    Karl Bayer

    BOKU University, Austria

    2 publications · 97 citations

    2

    h-index

1–5 of 146

Institutions

56

  1. University of Colorado Boulder

    Boulder, United States

    3 h-index

    12 publications

    3.3K citations

  2. BOKU University

    Vienna, Austria

    2 h-index

    10 publications

    396 citations

  3. Universitat Autònoma de Barcelona

    Cerdanyola del Vallès, Spain

    2 h-index

    7 publications

    658 citations

  4. J.C. Bose University of Science & Technology, YMCA

    Faridabad, India

    1 h-index

    1 publications

    37 citations

  5. Beijing University of Chemical Technology

    Beijing, China

    1 h-index

    1 publications

    199 citations

  6. Bioprocessing Technology Institute

    Singapore, Singapore

    1 h-index

    4 publications

    156 citations

  7. Uppsala University

    Uppsala, Sweden

    1 h-index

    2 publications

    120 citations

  8. Gyeongsang National University

    Jinju-si, South Korea

    1 h-index

    2 publications

    28 citations

1–8 of 56

Venues

  1. Biotechnology Progress

    3 publications · 141 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 174 citations

    2

    h-index

  3. Applied Microbiology and Biotechnology

    2 publications · 82 citations

    2

    h-index

  4. Biotechnology and Bioengineering

    2 publications · 635 citations

    2

    h-index

  5. Nature Communications

    2 publications · 109 citations

    2

    h-index

1–5