Concepedia

Mediator Complex Structure

Mediator Complex Structure is a macromolecular assembly that functions as a transcriptional coactivator complex, distinguished by its modular organization of head, middle, tail, and kinase submodules enabling the integration and transduction of regulatory signals from transcription factors to RNA polymerase II.

95

Publications

7K

Citations

479

Authors

181

Institutions

Publications per year

2017–2026

24

Parents

Publications

95

Conserved Structures of Mediator and RNA Polymerase II Holoenzyme

Francisco J. Asturias, Yi Jiang, Lawrence C. Myers et al. · Science · 1999 · 275 citations

, , +17

Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

Philip J. Robinson, Michael J. Trnka, David Bushnell et al. · Cell · 2016 · 242 citations · Full text

, , +10

The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II

Hans Elmlund, Vera Baraznenok, Martin Lindahl et al. · Proceedings of the National Academy of Sciences · 2006 · 232 citations · Full text

, , +17

A high resolution protein interaction map of the yeast Mediator complex

Benjamin Guglielmi · Nucleic Acids Research · 2004 · 226 citations · Full text

, , +17

Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex

Kuang‐Lei Tsai, Chieri Tomomori‐Sato, Shigeo Sato et al. · Cell · 2014 · 219 citations · Full text

, , +16

1–5 of 95

Authors

479

  1. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    9 publications · 654 citations

    9

    h-index

  2. FJ
    Francisco J. Asturias

    Scripps Research Institute, United States

    8 publications · 1.2K citations

    8

    h-index

  3. RD
    Roger D. Kornberg

    Stanford University, United States

    8 publications · 1.3K citations

    8

    h-index

  4. CM
    Claes M. Gustafsson

    University of Gothenburg, Sweden

    6 publications · 842 citations

    6

    h-index

  5. LL
    Laurent Larivière

    Ludwig-Maximilians-Universität München, Germany

    6 publications · 481 citations

    6

    h-index

1–5 of 479

Institutions

181

  1. Stanford University

    Stanford, United States

    9 h-index

    42 publications

    7K citations

  2. Ludwig-Maximilians-Universität München

    Munich, Germany

    7 h-index

    46 publications

    3.3K citations

  3. Rockefeller University

    New York, United States

    7 h-index

    36 publications

    4.5K citations

  4. Max Planck Society

    Munich, Germany

    7 h-index

    8 publications

    520 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    38 publications

    921 citations

  6. Scripps Research Institute

    San Diego, United States

    6 h-index

    21 publications

    3.5K citations

  7. Center for Integrated Protein Science Munich

    Munich, Germany

    6 h-index

    40 publications

    2.9K citations

  8. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    6 h-index

    16 publications

    1.6K citations

1–8 of 181

Venues

  1. Molecular and Cellular Biology

    MCB · 11 publications · 709 citations

    11

    h-index

  2. Journal of Biological Chemistry

    JBC · 9 publications · 572 citations

    9

    h-index

  3. Nucleic Acids Research

    8 publications · 564 citations

    8

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 939 citations

    7

    h-index

  5. Nature Structural & Molecular Biology

    5 publications · 563 citations

    5

    h-index

1–5