Concepedia

Mediator Complex Regulation

Mediator Complex Regulation is a molecular mechanism that directs the assembly and functional interaction of RNA polymerase II with transcription factors by serving as a coactivator complex that modulates signal transmission from gene-specific regulators to the basal transcription machinery.

83

Publications

5.4K

Citations

545

Authors

174

Institutions

Publications per year

2017–2026

24

Parents

Publications

83

MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling

Sidong Huang, Michael Hölzel, Theo Knijnenburg et al. · Cell · 2012 · 432 citations · Full text

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The <i>Arabidopsis</i> Mediator Subunit MED25 Differentially Regulates Jasmonate and Abscisic Acid Signaling through Interacting with the MYC2 and ABI5 Transcription Factors

Rong Chen, Hongling Jiang, Lin Li et al. · The Plant Cell · 2012 · 397 citations · Full text

, , +17

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

Matthew T. Knuesel, Krista Meyer, Carrie Bernecky et al. · Genes & Development · 2009 · 348 citations · Full text

, , +16

A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in <i>C. elegans</i>

Stefan Taubert, Marc R. Van Gilst, Malene Hansen et al. · Genes & Development · 2006 · 258 citations · Full text

, , +17

Mediator Complex Regulates Alternative mRNA Processing via the MED23 Subunit

Yan Huang, Wencheng Li, Yao Xiao et al. · Molecular Cell · 2012 · 167 citations · Full text

, , +12

1–5 of 83

Authors

545

  1. IS
    Isabella Syring

    University Hospital Bonn, Germany

    5 publications · 198 citations

    5

    h-index

  2. WV
    Wenzel Vogel

    University Hospital Bonn, Germany

    4 publications · 185 citations

    4

    h-index

  3. JE
    Jörg Ellinger

    University Hospital Bonn, Germany

    4 publications · 85 citations

    4

    h-index

  4. SC
    Stefan C. Müller

    University Hospital Bonn, Germany

    4 publications · 85 citations

    4

    h-index

  5. JB
    Johannes Brägelmann

    University of Cologne, Germany

    4 publications · 185 citations

    4

    h-index

1–5 of 545

Institutions

174

  1. University Hospital Bonn

    Bonn, Germany

    5 h-index

    38 publications

    1.5K citations

  2. Albert Einstein College of Medicine

    Bronx, United States

    5 h-index

    18 publications

    704 citations

  3. Rutgers, The State University of New Jersey

    New Brunswick, United States

    4 h-index

    7 publications

    649 citations

  4. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    37 publications

    6.7K citations

  5. Rockefeller University

    New York, United States

    4 h-index

    15 publications

    1.6K citations

  6. Center for Excellence in Molecular Cell Science

    Shanghai, China

    3 h-index

    13 publications

    1.5K citations

  7. Purdue University West Lafayette

    West Lafayette, United States

    3 h-index

    16 publications

    1.2K citations

  8. Shanghai Institutes for Biological Sciences

    Shanghai, China

    3 h-index

    16 publications

    1.7K citations

1–8 of 174

Venues

  1. Journal of Biological Chemistry

    JBC · 10 publications · 621 citations

    10

    h-index

  2. Genes & Development

    4 publications · 760 citations

    4

    h-index

  3. Molecular and Cellular Biology

    MCB · 4 publications · 287 citations

    4

    h-index

  4. PLANT PHYSIOLOGY

    3 publications · 124 citations

    3

    h-index

  5. PLoS Genetics

    3 publications · 84 citations

    3

    h-index

1–5