Concepedia

Mechanism-based Modeling

Mechanism-Based Modeling is a computational or mathematical framework that quantitatively describes drug response by explicitly representing the underlying biological and pharmacological processes governing drug action, thereby distinguishing it from empirical or phenomenological approaches through its reliance on causal mechanistic principles.

204

Publications

11.3K

Citations

798

Authors

368

Institutions

Publications per year

2017–2026

84

Variants

Mechanistic Modeling

Parents

Publications

204

Malachite green adsorption by rattan sawdust: Isotherm, kinetic and mechanism modeling

B.H. Hameed, Mohammad I. El‐Khaiary · Journal of Hazardous Materials · 2008 · 411 citations

, , +14

Adsorptive removal of cationic methylene blue and anionic Congo red dyes using wet-torrefied microalgal biochar: Equilibrium, kinetic and mechanism modeling

Kai Yu, Xin Jiat Lee, Hwai Chyuan Ong et al. · Environmental Pollution · 2020 · 303 citations

, , +17

Equilibrium, kinetics and mechanism modeling and simulation of basic and acid dyes sorption onto jute fiber carbon: Eosin yellow, malachite green and crystal violet single component systems

K. Porkodi, K. Vasanth Kumar · Journal of Hazardous Materials · 2006 · 299 citations

, , +8

Exposing the behavioral gambit: the evolution of learning and decision rules

Tim W. Fawcett, Steven Hamblin, Luc‐Alain Giraldeau · Behavioral Ecology · 2012 · 294 citations · Full text

, , +13

A Structure-Based Mechanism for Copper−Zinc Superoxide Dismutase<sup>,</sup>

P. John Hart, Melinda Balbirnie, N.L. Ogihara et al. · Biochemistry · 1999 · 271 citations

, , +13

1–5 of 204

Authors

798

  1. JB
    Jürgen B. Bulitta

    Monash University, Australia

    8 publications · 442 citations

    8

    h-index

  2. CB
    Cornelia B. Landersdorfer

    Monash University, Australia

    6 publications · 276 citations

    6

    h-index

  3. MD
    Meindert Danhof

    Leiden University, Netherlands

    5 publications · 208 citations

    5

    h-index

  4. PH
    Piet H. van der Graaf

    Centre for Human Drug Research, Netherlands

    5 publications · 223 citations

    5

    h-index

  5. MK
    Mohit Kumar Jolly

    Indian Institute of Science Bangalore, India

    5 publications · 248 citations

    5

    h-index

1–5 of 798

Institutions

368

  1. University at Buffalo, State University of New York

    Buffalo, United States

    11 h-index

    34 publications

    2.4K citations

  2. University of Florida

    Gainesville, United States

    11 h-index

    23 publications

    698 citations

  3. Centre for Human Drug Research

    Leiden, The Netherlands

    9 h-index

    16 publications

    594 citations

  4. Monash University

    Melbourne, Australia

    7 h-index

    36 publications

    1.5K citations

  5. Johns Hopkins University

    Baltimore, United States

    7 h-index

    19 publications

    2.1K citations

  6. Leiden University

    Leiden, The Netherlands

    6 h-index

    12 publications

    248 citations

  7. University of Michigan

    Ann Arbor, United States

    6 h-index

    16 publications

    1.6K citations

  8. Uppsala University

    Uppsala, Sweden

    6 h-index

    16 publications

    546 citations

1–8 of 368

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 9 publications · 468 citations

    9

    h-index

  2. CPT Pharmacometrics & Systems Pharmacology

    PSP · 7 publications · 410 citations

    7

    h-index

  3. 5

    h-index

  4. PubMed

    Repository · 5 publications · 233 citations

    5

    h-index

  5. Clinical Pharmacology & Therapeutics

    CPT · 5 publications · 388 citations

    5

    h-index

1–5