Concepedia

Mannose-6-phosphate Sorting

Mannose-6-Phosphate Sorting is a lysosomal trafficking mechanism that directs newly synthesized lysosomal hydrolases to lysosomes by recognizing mannose-6-phosphate residues on their N-glycans and mediating their receptor-dependent transport from the Golgi apparatus to endolysosomal compartments.

24

Publications

2.5K

Citations

118

Authors

64

Institutions

Publications per year

2017–2026

1

Parents

Publications

24

Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling

Philip D. Stahl, Paul H. Schlesinger, Elaine Sigardson et al. · Cell · 1980 · 573 citations

, , +15

Sorting of Mannose 6-Phosphate Receptors Mediated by the GGAs

Rosa Puertollano, R. Claudio Aguilar, Inna Gorshkova et al. · Science · 2001 · 389 citations

, , +17

Mannose-6-phosphate receptors for lysosomal enzymes cycle between the Golgi complex and endosomes.

Wendy J. Brown, Joseph Goodhouse, M G Farquhar · The Journal of Cell Biology · 1986 · 273 citations · Full text

, , +15

Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblasts.

Jonathan N. Glickman, Stuart Kornfeld · The Journal of Cell Biology · 1993 · 142 citations · Full text

, , +17

Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

Yanping Zhu, M.D.L. Suits, Andrew J. Thompson et al. · Nature Chemical Biology · 2009 · 141 citations · Full text

, , +14

1–5 of 24

Authors

118

  1. TB
    Thomas Braulke

    Universität Hamburg, Germany

    3 publications · 136 citations

    3

    h-index

  2. SK
    Stuart Kornfeld

    Washington University in St. Louis, United States

    3 publications · 341 citations

    3

    h-index

  3. CB
    Christian Böker

    University of Göttingen, Germany

    2 publications · 67 citations

    2

    h-index

  4. WJ
    Wendy J. Brown

    The University of Queensland, Australia

    2 publications · 389 citations

    2

    h-index

  5. MG
    M G Farquhar

    Yale University, United States

    2 publications · 389 citations

    2

    h-index

1–5 of 118

Institutions

64

  1. Washington University in St. Louis

    St Louis, United States

    4 h-index

    11 publications

    3.1K citations

  2. University of Göttingen

    Göttingen, Germany

    3 h-index

    12 publications

    489 citations

  3. McGill University

    Montreal, Canada

    2 h-index

    5 publications

    139 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    6 publications

    687 citations

  5. Children's Hospital 1

    Ho Chi Minh City, Vietnam

    1 h-index

    8 publications

    248 citations

  6. Boston Children's Hospital

    Boston, United States

    1 h-index

    1 publications

    60 citations

  7. University Medical Center Hamburg-Eppendorf

    Hamburg, Germany

    1 h-index

    8 publications

    248 citations

  8. University of Georgia

    Athens, United States

    1 h-index

    3 publications

    423 citations

1–8 of 64

Venues

  1. The Journal of Cell Biology

    JCB · 6 publications · 761 citations

    6

    h-index

  2. Molecular Biology of the Cell

    MBC · 2 publications · 59 citations

    2

    h-index

  3. Journal of Biological Chemistry

    JBC · 2 publications · 83 citations

    2

    h-index

  4. Blood

    1 publications · 11 citations

    1

    h-index

  5. The Journal of Biochemistry

    JB · 1 publications · 14 citations

    1

    h-index

1–5