Concepedia

Mammalian Display Libraries

Mammalian Display Libraries is a recombinant antibody display technology that utilizes mammalian cells to express antibody fragments on the cell surface, enabling the functional screening and selection of high-affinity binders in a eukaryotic environment that supports native protein folding and post-translational modifications.

11

Publications

506

Citations

88

Authors

28

Institutions

Publications per year

2017–2026

8

Parents

Publications

11

Myocardial perfusion defects and associated systemic ventricular dysfunction in congenitally corrected transposition of the great arteries

Tim Hornung, E Bernard, Edgar Jaeggi et al. · Heart · 1998 · 107 citations · Full text

, , +17

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

Derek M. Mason, Cédric R. Weber, Cristina Parola et al. · Nucleic Acids Research · 2018 · 87 citations · Full text

, , +17

Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

Michael R. Dyson, Edward W. Masters, Deividas Pazeraitis et al. · mAbs · 2020 · 67 citations · Full text

, , +17

A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing

Kothai Parthiban, Rajika L. Perera, Maheen Sattar et al. · mAbs · 2019 · 57 citations · Full text

, , +17

Deep learning enables therapeutic antibody optimization in mammalian cells by deciphering high-dimensional protein sequence space

Derek M. Mason, Simon Friedensohn, Cédric R. Weber et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 54 citations · Full text

, , +17

1–5 of 11

Authors

88

  1. KP
    Kothai Parthiban

    University of Cambridge, United Kingdom

    2 publications · 124 citations

    2

    h-index

  2. RA
    Rachael A. Leah

    Universidad de Costa Rica, Costa Rica

    2 publications · 124 citations

    2

    h-index

  3. JM
    John McCafferty

    University of Cambridge, United Kingdom

    2 publications · 124 citations

    2

    h-index

  4. MR
    Michael R. Dyson

    University of Cambridge, United Kingdom

    2 publications · 124 citations

    2

    h-index

  5. RL
    Rajika L. Perera

    University of Cambridge, United Kingdom

    2 publications · 124 citations

    2

    h-index

1–5 of 88

Institutions

28

  1. ETH Zurich

    Zurich, Switzerland

    2 h-index

    14 publications

    987 citations

  2. BOKU University

    Vienna, Austria

    2 h-index

    9 publications

    372 citations

  3. Computing Center

    Khabarovsk, Russia

    1 h-index

    1 publications

    67 citations

  4. Cold Spring Harbor Laboratory

    Cold Spring Harbor, United States

    1 h-index

    1 publications

    67 citations

  5. Japan Society for the Promotion of Science

    Tokyo, Japan

    1 h-index

    1 publications

    17 citations

  6. École Polytechnique Fédérale de Lausanne

    Lausanne, Switzerland

    1 h-index

    2 publications

    108 citations

  7. Scripps Research Institute

    San Diego, United States

    1 h-index

    6 publications

    84 citations

  8. University of Oxford

    Oxford, United Kingdom

    1 h-index

    1 publications

    31 citations

1–8 of 28

Venues

  1. Journal of Biological Chemistry

    JBC · 2 publications · 57 citations

    2

    h-index

  2. mAbs

    2 publications · 124 citations

    2

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 54 citations

    1

    h-index

  4. Heart

    1 publications · 107 citations

    1

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 1 publications · 17 citations

    1

    h-index

1–5