Concepedia

Macrocyclic Peptidomimetics

Macrocyclic Peptidomimetics is a peptidomimetic design strategy that involves the construction of conformationally constrained, ring-containing scaffolds to emulate peptide secondary structures while enhancing metabolic stability and target binding affinity.

294

Publications

11.2K

Citations

1.7K

Authors

408

Institutions

Publications per year

2017–2026

60

Parents

Publications

294

Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library

Y. Yamagishi, Ikuo Shoji, Shoji Miyagawa et al. · Chemistry & Biology · 2011 · 356 citations

, , +14

Macrocyclic Peptidomimetics Forcing Peptides into Bioactive Conformations

David P. Fairlie, Giovanni Abbenante, Darren R. March · Current Medicinal Chemistry · 1995 · 208 citations

, , +17

Molecular‐Size Reduction of a Potent CXCR4‐Chemokine Antagonist Using Orthogonal Combination of Conformation‐ and Sequence‐Based Libraries

Nobutaka Fujii, Shinya Oishi, Kenichi Hiramatsu et al. · Angewandte Chemie International Edition · 2003 · 204 citations

, , +17

Oxadiazole grafts in peptide macrocycles

John R. Frost, Conor C. G. Scully, Andrei K. Yudin · Nature Chemistry · 2016 · 177 citations

, , +9

Synthetic Macrocyclic Peptidomimetics as Tunable pH Probes for the Fluorescence Imaging of Acidic Organelles in Live Cells

Francisco Galindo, M. Isabel Burguete, Laura Vigara et al. · Angewandte Chemie International Edition · 2005 · 165 citations

, , +17

1–5 of 294

Authors

1.7K

  1. DP
    David P. Fairlie

    The University of Queensland, Australia

    9 publications · 572 citations

    9

    h-index

  2. SV
    Santiago V. Luis

    Universitat Jaume I, Spain

    8 publications · 557 citations

    8

    h-index

  3. MI
    M. Isabel Burguete

    Universitat Jaume I, Spain

    7 publications · 539 citations

    7

    h-index

  4. DP
    Dehua Pei

    The Ohio State University, United States

    7 publications · 212 citations

    7

    h-index

  5. DR
    Darren R. March

    The University of Queensland, Australia

    6 publications · 449 citations

    6

    h-index

1–5 of 1.7K

Institutions

408

  1. The University of Queensland

    Brisbane, Australia

    12 h-index

    69 publications

    3.9K citations

  2. The University of Tokyo

    Tokyo, Japan

    8 h-index

    28 publications

    3.9K citations

  3. University of Naples Federico II

    Naples, Italy

    8 h-index

    35 publications

    720 citations

  4. Universitat Jaume I

    Castellon, Spain

    7 h-index

    29 publications

    1.9K citations

  5. The Ohio State University

    Columbus, United States

    7 h-index

    24 publications

    850 citations

  6. University of Milan

    Milan, Italy

    7 h-index

    30 publications

    721 citations

  7. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    6 h-index

    71 publications

    1.6K citations

  8. University of Toronto

    Toronto, Canada

    6 h-index

    24 publications

    1.2K citations

1–8 of 408

Venues

  1. Bioorganic & Medicinal Chemistry Letters

    43 publications · 1.1K citations

    21

    h-index

  2. Journal of Medicinal Chemistry

    28 publications · 1.1K citations

    20

    h-index

  3. Organic Letters

    OL · 21 publications · 664 citations

    16

    h-index

  4. Bioorganic & Medicinal Chemistry

    20 publications · 534 citations

    15

    h-index

  5. Journal of the American Chemical Society

    JACS · 13 publications · 892 citations

    13

    h-index

1–5