Darren R. March

Macrocyclic Peptidomimetics Forcing Peptides into Bioactive Conformations

David P. Fairlie, Giovanni Abbenante, Darren R. March · Current Medicinal Chemistry · 1995 · 208 citations

Conformational Entropy, Peptide Engineering, Chemical Biology +16

Conformational Selection of Inhibitors and Substrates by Proteolytic Enzymes:  Implications for Drug Design and Polypeptide Processing

David P. Fairlie, Joel D. A. Tyndall, Robert C. Reid et al. · Journal of Medicinal Chemistry · 2000 · 152 citations · Full text

Protein Assembly, Biomolecular Structure Prediction, Molecular Biology +21

Potent Cyclic Antagonists of the Complement C5a Receptor on Human Polymorphonuclear Leukocytes. Relationships between Structures and Activity

Darren R. March, Lavinia M. Proctor, Martin J. Stoermer et al. · Molecular Pharmacology · 2004 · 112 citations

Analogues of SB-203207 as inhibitors of tRNA synthetases

Martin G. Banwell, Curtis F. Crasto, Christopher J. Easton et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 79 citations · Full text

Medicine, Trna Synthetases, Pharmacology +2

Substrate-Based Cyclic Peptidomimetics of Phe-Ile-Val That Inhibit HIV-1 Protease Using a Novel Enzyme-Binding Mode

Darren R. March, Giovanni Abbenante, Douglas A. Bergman et al. · Journal of the American Chemical Society · 1996 · 76 citations

Peptide Engineering, Molecular Biology, Peptide Substrates +20