Concepedia

Lysosomal Proteolysis

Lysosomal Proteolysis is a proteolytic process in which intracellular macromolecules are degraded through the action of hydrolytic enzymes within the acidic compartment of the lysosome.

1K

Publications

74.7K

Citations

3.8K

Authors

996

Institutions

Publications per year

2017–2026

104

Parents

Publications

1K

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells.

Tamotsu Yoshimori, Akira Yamamoto, Yoshinori Moriyama et al. · Journal of Biological Chemistry · 1991 · 1.4K citations · Full text

, , +14

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

Ju‐Hyun Lee, Wai Haung Yu, Asok Kumar et al. · Cell · 2010 · 1.2K citations · Full text

, , +16

Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency

Bruce D. Gelb, Guo‐Ping Shi, Harold A. Chapman et al. · Science · 1996 · 1K citations

, , +17

A Role for a 70-Kilodalton Heat Shock Protein in Lysosomal Degradation of Intracellular Proteins

Hui-Ling Chiang, Stanley R. Terlecky, Charles P. Plant et al. · Science · 1989 · 967 citations

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A Receptor for the Selective Uptake and Degradation of Proteins by Lysosomes

Ana María Cuervo, J. Fred Dice · Science · 1996 · 953 citations

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1–5 of 1K

Authors

3.8K

  1. AM
    Ana María Cuervo

    Albert Einstein College of Medicine, United States

    14 publications · 4.6K citations

    14

    h-index

  2. GW
    Gerald Weissmann

    New York University, United States

    14 publications · 2.3K citations

    14

    h-index

  3. JF
    J. Fred Dice

    Tufts University, United States

    14 publications · 3.7K citations

    14

    h-index

  4. EK
    Eiki Kominami

    Juntendo University, Japan

    16 publications · 799 citations

    13

    h-index

  5. AL
    Alfred L. Goldberg

    Harvard University, United States

    12 publications · 1.9K citations

    12

    h-index

1–5 of 3.8K

Institutions

996

  1. Harvard University

    Cambridge, United States

    23 h-index

    76 publications

    9.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    49 publications

    3.4K citations

  3. University of Freiburg

    Freiburg im Breisgau, Germany

    15 h-index

    41 publications

    3.4K citations

  4. Inserm

    Paris, France

    15 h-index

    46 publications

    3.5K citations

  5. New York University

    New York, United States

    15 h-index

    40 publications

    6.7K citations

  6. Tufts University

    Medford, United States

    15 h-index

    36 publications

    9.5K citations

  7. Juntendo University

    Tokyo, Japan

    13 h-index

    44 publications

    3.6K citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    13 h-index

    42 publications

    3K citations

1–8 of 996

Venues

  1. Journal of Biological Chemistry

    JBC · 86 publications · 8.8K citations

    55

    h-index

  2. Biochemical Journal

    BJ · 45 publications · 3.6K citations

    29

    h-index

  3. PubMed

    Repository · 65 publications · 3.3K citations

    28

    h-index

  4. The Journal of Cell Biology

    JCB · 23 publications · 3.3K citations

    23

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 24 publications · 3.3K citations

    20

    h-index

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