Concepedia

Lysosomal Enzyme Sorting

Lysosomal Enzyme Sorting is a cellular trafficking mechanism that directs hydrolytic enzymes from the Golgi apparatus to lysosomes via specific recognition of mannose-6-phosphate tags on the enzymes, ensuring their proper subcellular localization and function.

54

Publications

4.6K

Citations

182

Authors

68

Institutions

Publications per year

2017–2026

0

Parents

Publications

54

Cooperation of GGAs and AP-1 in Packaging MPRs at the Trans-Golgi Network

Balraj Doray, Pradipta Ghosh, Janice Griffith et al. · Science · 2002 · 312 citations

, , +17

Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network.

Markus A. Riederer, Thierry Soldati, Allan D. Shapiro et al. · The Journal of Cell Biology · 1994 · 310 citations · Full text

, , +17

Mannose 6–Phosphate Receptors Are Sorted from Immature Secretory Granules via Adaptor Protein AP-1, Clathrin, and Syntaxin 6–positive Vesicles

Judith Klumperman, Regina Kuliawat, Janice Griffith et al. · The Journal of Cell Biology · 1998 · 291 citations · Full text

, , +17

Binding of GGA2 to the Lysosomal Enzyme Sorting Motif of the Mannose 6-Phosphate Receptor

Yunxiang Zhu, Balraj Doray, Anssi Poussu et al. · Science · 2001 · 282 citations

, , +17

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

Peter Lobel, K Fujimoto, Richard D. Ye et al. · Cell · 1989 · 273 citations

, , +16

1–5 of 54

Authors

182

  1. SK
    Stuart Kornfeld

    Washington University in St. Louis, United States

    7 publications · 1.3K citations

    7

    h-index

  2. TB
    Thomas Braulke

    Universität Hamburg, Germany

    7 publications · 377 citations

    7

    h-index

  3. JA
    James A. Cardelli

    Louisiana State University Health Sciences Center Shreveport, United States

    6 publications · 245 citations

    6

    h-index

  4. PL
    Peter Lobel

    Rutgers, The State University of New Jersey, United States

    6 publications · 786 citations

    6

    h-index

  5. KV
    Kurt Von Figura

    University of Göttingen, Germany

    6 publications · 329 citations

    6

    h-index

1–5 of 182

Institutions

68

  1. Washington University in St. Louis

    St Louis, United States

    8 h-index

    22 publications

    4.6K citations

  2. University of Göttingen

    Göttingen, Germany

    6 h-index

    15 publications

    361 citations

  3. Louisiana State University in Shreveport

    Shreveport, United States

    5 h-index

    14 publications

    737 citations

  4. Saint Louis University

    St Louis, United States

    3 h-index

    11 publications

    529 citations

  5. European Molecular Biology Laboratory

    Hamburg, Germany

    3 h-index

    14 publications

    1.1K citations

  6. University Hospital and Clinics

    Lafayette, United States

    2 h-index

    6 publications

    102 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    5 publications

    242 citations

  8. Health and Human Development (2HD) Research Network

    Douala, Cameroon

    2 h-index

    6 publications

    402 citations

1–8 of 68

Venues

  1. Journal of Biological Chemistry

    JBC · 18 publications · 1.2K citations

    16

    h-index

  2. The Journal of Cell Biology

    JCB · 9 publications · 1.6K citations

    9

    h-index

  3. Experimental Cell Research

    ECR · 3 publications · 79 citations

    3

    h-index

  4. Molecular Biology of the Cell

    MBC · 3 publications · 181 citations

    3

    h-index

  5. Science

    2 publications · 594 citations

    2

    h-index

1–5