Concepedia

Loop Refinement

Loop Refinement is a computational method in structural biology that specifically optimizes the three-dimensional conformation of loop regions in protein models by iteratively adjusting backbone and side-chain geometries to improve stereochemical accuracy and fit to experimental or predicted constraints.

20

Publications

1.1K

Citations

73

Authors

34

Institutions

Publications per year

2017–2026

0

Parents

Publications

20

Engineering of Flexible Loops in Enzymes

Bettina M. Nestl, Bernhard Hauer · ACS Catalysis · 2014 · 232 citations

, , +14

Effective protein model structure refinement by loop modeling and overall relaxation

Gyu Rie Lee, Lim Heo, Chaok Seok · Proteins Structure Function and Bioinformatics · 2015 · 139 citations · Full text

, , +16

The FALC-Loop web server for protein loop modeling

Jin Hwan Ko, Doheon Lee, Hahnbeom Park et al. · Nucleic Acids Research · 2011 · 111 citations · Full text

, , +17

Multicopy Crystallographic Refinement of a Relaxed Glutamine Synthetase from <i>Mycobacterium tuberculosis</i> Highlights Flexible Loops in the Enzymatic Mechanism and Its Regulation

Harindarpal S. Gill, Gaston M.U. Pfluegl, David Eisenberg · Biochemistry · 2002 · 91 citations

, , +17

Toward better refinement of comparative models: Predicting loops in inexact environments

Benjamin D. Sellers, Kai Zhu, Suwen Zhao et al. · Proteins Structure Function and Bioinformatics · 2008 · 84 citations · Full text

, , +17

1–5 of 20

Authors

73

  1. RA
    Richard A. Friesner

    Columbia University, United States

    2 publications · 154 citations

    2

    h-index

  2. CS
    Chaok Seok

    Seoul National University, South Korea

    2 publications · 250 citations

    2

    h-index

  3. KZ
    Kai Zhu

    Schrodinger (United States), United States

    2 publications · 154 citations

    2

    h-index

  4. MP
    Matthew P. Jacobson

    University of California, San Francisco, United States

    2 publications · 100 citations

    2

    h-index

  5. BD
    Benjamin D. Sellers

    University of California, San Francisco, United States

    2 publications · 100 citations

    2

    h-index

1–5 of 73

Institutions

34

  1. University of California, San Francisco

    San Francisco, United States

    2 h-index

    5 publications

    216 citations

  2. Seoul National University

    Seoul, South Korea

    2 h-index

    8 publications

    972 citations

  3. Columbia University

    New York, United States

    2 h-index

    5 publications

    392 citations

  4. La Roche College

    Pittsburgh, United States

    1 h-index

    7 publications

    119 citations

  5. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    1 h-index

    4 publications

    112 citations

  6. National Institute of Biomedical Innovation, Health and Nutrition

    Tsukuba, Japan

    1 h-index

    2 publications

    106 citations

  7. University of New Mexico

    Albuquerque, United States

    1 h-index

    5 publications

    555 citations

  8. Japan Advanced Institute of Science and Technology

    Nomi Shi, Japan

    1 h-index

    2 publications

    32 citations

1–8 of 34

Venues

  1. Proteins Structure Function and Bioinformatics

    6 publications · 377 citations

    6

    h-index

  2. Biopolymers

    1 publications · 36 citations

    1

    h-index

  3. Tetrahedron

    1 publications · 17 citations

    1

    h-index

  4. Journal of Biomolecular NMR

    1 publications · 40 citations

    1

    h-index

  5. Nucleic Acids Research

    1 publications · 111 citations

    1

    h-index

1–5