Concepedia

Loop Extrusion Models

Loop Extrusion Models is a computational or theoretical framework that specifies the mechanistic principles and dynamic rules governing the formation and regulation of chromatin loops by molecular motors such as cohesin and condensin within the context of genome architecture.

38

Publications

6.7K

Citations

181

Authors

103

Institutions

Publications per year

2017–2026

35

Parents

Publications

38

Formation of Chromosomal Domains by Loop Extrusion

Geoffrey Fudenberg, Maxim Imakaev, Carolyn Lu et al. · Cell Reports · 2016 · 2.2K citations · Full text

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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

Adrian L. Sanborn, Suhas S.P. Rao, Su-Chen Huang et al. · Proceedings of the National Academy of Sciences · 2015 · 1.9K citations · Full text

, , +17

Self-organization of domain structures by DNA-loop-extruding enzymes

Elmira Alipour, John F. Marko · Nucleic Acids Research · 2012 · 580 citations · Full text

, , +17

Emerging Evidence of Chromosome Folding by Loop Extrusion

Geoffrey Fudenberg, Nezar Abdennur, Maxim Imakaev et al. · Cold Spring Harbor Symposia on Quantitative Biology · 2017 · 331 citations · Full text

, , +16

Chromosome organization by one-sided and two-sided loop extrusion

Edward J. Banigan, Aafke A. van den Berg, Hugo B. Brandão et al. · eLife · 2020 · 163 citations · Full text

, , +17

1–5 of 38

Authors

181

  1. LA
    Leonid A. Mirny

    Massachusetts Institute of Technology, United States

    8 publications · 2.9K citations

    8

    h-index

  2. MI
    Maxim Imakaev

    Massachusetts Institute of Technology, United States

    5 publications · 2.6K citations

    5

    h-index

  3. HB
    Hugo B. Brandão

    Massachusetts Institute of Technology, United States

    4 publications · 296 citations

    4

    h-index

  4. JF
    John F. Marko

    Northwestern University, United States

    4 publications · 900 citations

    4

    h-index

  5. RB
    Roman Barth

    Delft University of Technology, Netherlands

    3 publications · 191 citations

    3

    h-index

1–5 of 181

Institutions

103

  1. Massachusetts Institute of Technology

    Cambridge, United States

    11 h-index

    33 publications

    13.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    9 publications

    401 citations

  3. Delft University of Technology

    Delft, The Netherlands

    5 h-index

    23 publications

    1.6K citations

  4. Inserm

    Paris, France

    4 h-index

    10 publications

    299 citations

  5. Northwestern University

    Evanston, United States

    4 h-index

    4 publications

    900 citations

  6. Harvard University

    Cambridge, United States

    4 h-index

    23 publications

    15.7K citations

  7. Research Institute of Molecular Pathology

    Vienna, Austria

    3 h-index

    8 publications

    556 citations

  8. Vienna Biocenter

    Vienna, Austria

    3 h-index

    8 publications

    556 citations

1–8 of 103

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 7 publications · 187 citations

    7

    h-index

  2. Cell Reports

    4 publications · 2.3K citations

    4

    h-index

  3. eLife

    4 publications · 328 citations

    4

    h-index

  4. Nucleic Acids Research

    3 publications · 772 citations

    3

    h-index

  5. Nature Communications

    3 publications · 110 citations

    3

    h-index

1–5