Concepedia

Light Chain Libraries

Light Chain Libraries is a type of antibody library that consists of a diverse collection of DNA sequences encoding the light chain variable regions of antibodies, enabling the systematic exploration and selection of antigen-specific binding partners in conjunction with fixed or paired heavy chains.

33

Publications

1.2K

Citations

162

Authors

72

Institutions

Publications per year

2017–2026

5

Parents

Publications

33

Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries.

Angray S. Kang, Terri Jones, Dennis R. Burton · Proceedings of the National Academy of Sciences · 1991 · 143 citations

, , +17

Yeast mating for combinatorial Fab library generation and surface display

Jane Weaver-Feldhaus, Jianlong Lou, James R. Coleman et al. · FEBS Letters · 2004 · 110 citations

, , +17

Optimization of primers for cloning libraries of mouse immunoglobulin genes using the polymerase chain reaction

Catherine Kettleborough, José W. Saldanha, Keith H. Ansell et al. · European Journal of Immunology · 1993 · 82 citations

, , +15

Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating

Jianlong Lou, Isin N. Geren, Carmen García‐Rodríguez et al. · Protein Engineering Design and Selection · 2010 · 63 citations · Full text

, , +17

A VHH That Neutralizes the Zinc Metalloproteinase Activity of Botulinum Neurotoxin Type A

Jeeraphong Thanongsaksrikul, Potjanee Srimanote, Santi Maneewatch et al. · Journal of Biological Chemistry · 2010 · 60 citations · Full text

, , +17

1–5 of 33

Authors

162

  1. VN
    Valentina N. Buneva

    Siberian Branch of the Russian Academy of Sciences, Russia

    3 publications · 73 citations

    3

    h-index

  2. JG
    Julius Grzeschik

    Technische Universität Darmstadt, Germany

    3 publications · 92 citations

    3

    h-index

  3. GA
    Georgy A. Nevinsky

    Siberian Branch of the Russian Academy of Sciences, Russia

    3 publications · 73 citations

    3

    h-index

  4. HK
    Harald Kolmar

    Technische Universität Darmstadt, Germany

    3 publications · 92 citations

    3

    h-index

  5. JD
    James D. Marks

    University of California, San Francisco, United States

    3 publications · 201 citations

    3

    h-index

1–5 of 162

Institutions

72

  1. Institute of Chemical Biology and Fundamental Medicine

    Novosibirsk, Russia

    3 h-index

    10 publications

    242 citations

  2. Novosibirsk State University

    Novosibirsk, Russia

    3 h-index

    6 publications

    146 citations

  3. Technische Universität Darmstadt

    Darmstadt, Germany

    3 h-index

    12 publications

    344 citations

  4. Siberian Branch of the Russian Academy of Sciences

    Novosibirsk, Russia

    3 h-index

    10 publications

    242 citations

  5. Albert Einstein College of Medicine

    Bronx, United States

    2 h-index

    7 publications

    121 citations

  6. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    4 publications

    126 citations

  7. University of California, San Francisco

    San Francisco, United States

    2 h-index

    7 publications

    535 citations

  8. San Francisco General Hospital

    San Francisco, United States

    2 h-index

    8 publications

    598 citations

1–8 of 72

Venues

  1. The Journal of Immunology

    JI · 3 publications · 116 citations

    3

    h-index

  2. Journal of Molecular Recognition

    JMR · 2 publications · 53 citations

    2

    h-index

  3. PubMed

    Repository · 2 publications · 43 citations

    2

    h-index

  4. Protein Engineering Design and Selection

    PEDS · 2 publications · 73 citations

    2

    h-index

  5. 1

    h-index

1–5