Concepedia

Lethal Mutation Screening

Lethal Mutation Screening is a methodological approach in genetic analysis that identifies loss-of-function mutations leading to organismal death, thereby enabling the systematic assessment of gene essentiality within a given biological context.

27

Publications

1.1K

Citations

115

Authors

46

Institutions

Publications per year

2017–2026

1

Parents

Publications

27

MALE-SPECIFIC LETHAL MUTATIONS OF <i>DROSOPHILA MELANOGASTER</i>

John M. Belote, John C. Lucchesi · Genetics · 1980 · 181 citations · Full text

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Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans.

Kenneth J. Kemphues, Meredith Kusch, Nurit Wolf · Genetics · 1988 · 105 citations

, , +17

A <i>P</i>-Element Insertion Screen Identified Mutations in 455 Novel Essential Genes in Drosophila

Su‐Wan Oh, Tracy Kingsley, Hyun‐Hee Shin et al. · Genetics · 2003 · 90 citations

, , +11

GENETIC AND CYTOGENETIC ANALYSIS OF THE <i>ADH</i> REGION IN <i>DROSOPHILA MELANOGASTER</i>

Janis M. O’Donnell, Howard Mandel, Marc R. Krauss et al. · Genetics · 1977 · 71 citations · Full text

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Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations

Lawriston A. Wilson, Yung‐Hao Ching, Suzanne A. Hartford et al. · Genome Research · 2005 · 59 citations · Full text

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1–5 of 27

Authors

115

  1. SX
    Steven X. Hou

    National Cancer Institute, United States

    1 publications · 90 citations

    1

    h-index

  2. SY
    Shu Yi Chua

    Simon Fraser University, Canada

    1 publications · 19 citations

    1

    h-index

  3. SO
    Sean O’Rourke

    University of California, Davis, United States

    1 publications · 23 citations

    1

    h-index

  4. ZZ
    Zhiyu Zheng

    National Institutes of Health, United States

    1 publications · 90 citations

    1

    h-index

  5. YZ
    Ya-Ping Zhang

    Kunming Institute of Zoology, China

    1 publications · 24 citations

    1

    h-index

1–5 of 115

Institutions

46

  1. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    9 publications

    257 citations

  2. Harvard University

    Cambridge, United States

    3 h-index

    10 publications

    350 citations

  3. Bowling Green State University

    Bowling Green, United States

    2 h-index

    2 publications

    69 citations

  4. Cornell University

    Ithaca, United States

    2 h-index

    6 publications

    492 citations

  5. Johns Hopkins University

    Baltimore, United States

    2 h-index

    9 publications

    394 citations

  6. University of Utah

    Salt Lake City, United States

    1 h-index

    3 publications

    87 citations

  7. The University of Texas Health Science Center at Houston

    Houston, United States

    1 h-index

    2 publications

    48 citations

  8. Sun Yat-sen University Cancer Center

    Guangzhou, China

    1 h-index

    5 publications

    245 citations

1–8 of 46

Venues

  1. Genetics

    10 publications · 608 citations

    10

    h-index

  2. 2

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 64 citations

    2

    h-index

  4. Molecular and General Genetics MGG

    2 publications · 36 citations

    2

    h-index

  5. Genome Research

    GR · 2 publications · 108 citations

    2

    h-index

1–5