Concepedia

Lethal Giant Larvae Complex

The Lethal Giant Larvae Complex is a conserved protein regulatory complex that, as a key determinant of cell polarity, functions in asymmetric cell division and synaptic growth by regulating the spatial localization and activity of cell fate determinants and cytoskeletal components in neurons.

61

Publications

3.4K

Citations

286

Authors

121

Institutions

Publications per year

2017–2026

6

Variants

Lgl Complex

Parents

Publications

61

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization

Guy Tanentzapf · Nature Cell Biology · 2002 · 358 citations

, , +10

Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster.

Bernard M. Mechler, William McGinnis, W J Gehring · The EMBO Journal · 1985 · 251 citations · Full text

, , +17

Phosphorylation-Induced Autoinhibition Regulates the Cytoskeletal Protein Lethal (2) giant larvae

Joerg Betschinger, Frank Eisenhaber, Juergen A. Knoblich · Current Biology · 2005 · 151 citations · Full text

, , +13

Scribble associates with two polarity proteins, lgl2 and vangl2, via distinct molecular domains

Laura Kallay, Allison McNickle, Patrick Brennwald et al. · Journal of Cellular Biochemistry · 2006 · 151 citations

, , +13

Regulation of Lethal giant larvae by Dishevelled

Gretchen Dollar, Ursula Weber, Marek Mlodzik et al. · Nature · 2005 · 134 citations

, , +5

1–5 of 61

Authors

286

  1. DS
    Dennis Strand

    Johannes Gutenberg University Mainz, Germany

    6 publications · 385 citations

    6

    h-index

  2. BM
    Bernard M. Mechler

    German Cancer Research Center, Germany

    5 publications · 380 citations

    5

    h-index

  3. PB
    Patrick Brennwald

    University of North Carolina at Chapel Hill, United States

    4 publications · 289 citations

    4

    h-index

  4. ML
    Mingfa Li

    Shanghai Jiao Tong University, China

    3 publications · 62 citations

    3

    h-index

  5. KB
    Kwang‐Hyun Baek

    CHA University, South Korea

    3 publications · 93 citations

    3

    h-index

1–5 of 286

Institutions

121

  1. German Cancer Research Center

    Heidelberg, Germany

    5 h-index

    14 publications

    438 citations

  2. Johannes Gutenberg University Mainz

    Mainz, Germany

    5 h-index

    14 publications

    834 citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    7 publications

    421 citations

  4. DKFZ-ZMBH Alliance

    Heidelberg, Germany

    4 h-index

    11 publications

    405 citations

  5. University of California, San Francisco

    San Francisco, United States

    4 h-index

    17 publications

    604 citations

  6. Heidelberg University

    Heidelberg, Germany

    3 h-index

    5 publications

    57 citations

  7. CHA University

    Seongnam-si, South Korea

    3 h-index

    13 publications

    498 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    9 publications

    432 citations

1–8 of 121

Venues

  1. Developmental Biology

    4 publications · 239 citations

    4

    h-index

  2. Current Biology

    3 publications · 310 citations

    3

    h-index

  3. Journal of Biological Chemistry

    JBC · 3 publications · 107 citations

    3

    h-index

  4. Development

    3 publications · 182 citations

    3

    h-index

  5. Molecular Biology of the Cell

    MBC · 3 publications · 165 citations

    3

    h-index

1–5