Concepedia

Left-right Patterning Defects

Left-Right Patterning Defects is a developmental anomaly characterized by the disruption of the embryonic establishment of asymmetric organ positioning along the left-right axis, resulting in congenital malformations such as situs inversus or heterotaxy.

107

Publications

9.5K

Citations

598

Authors

211

Institutions

Publications per year

2017–2026

16

Variants

Left-right Asymmetry DefectsLeft-right Axis Defects

Parents

Publications

107

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

Albrecht Kramer-Zucker, Felix Olale, Courtney J. Haycraft et al. · Development · 2005 · 681 citations

, , +15

Dosage requirement of <i>Pitx2</i> for development of multiple organs

Philip J. Gage, Hoonkyo Suh, Sally A. Camper · Development · 1999 · 597 citations

, , +17

Function of Rieger syndrome gene in left–right asymmetry and craniofacial development

Mei-Fang Lu, C. Pressman, Rex B. Dyer et al. · Nature · 1999 · 504 citations

, , +16

Ciliogenesis and Left–Right Axis Defects in Forkhead Factor HFH-4–Null Mice

Steven L. Brody, Xiu Hua Yan, Mary K. Wuerffel et al. · American Journal of Respiratory Cell and Molecular Biology · 2000 · 359 citations

, , +9

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects

Richard N. Bamford, Erich Roessler, Rebecca D. Burdine et al. · Nature Genetics · 2000 · 351 citations

, , +12

1–5 of 107

Authors

598

  1. ML
    Michael Levin

    Tufts University, United States

    8 publications · 597 citations

    8

    h-index

  2. CL
    Cecilia Lo

    University of Pittsburgh, United States

    6 publications · 519 citations

    6

    h-index

  3. SM
    Stephanie M. Ware

    Cincinnati Children's Hospital Medical Center, United States

    6 publications · 600 citations

    6

    h-index

  4. BC
    Brett Casey

    Baylor College of Medicine, United States

    5 publications · 958 citations

    5

    h-index

  5. RD
    Rebecca D. Burdine

    Princeton University, United States

    4 publications · 529 citations

    4

    h-index

1–5 of 598

Institutions

211

  1. Harvard University

    Cambridge, United States

    11 h-index

    29 publications

    2.2K citations

  2. Massachusetts General Hospital

    Boston, United States

    7 h-index

    22 publications

    2.5K citations

  3. Baylor College of Medicine

    Houston, United States

    7 h-index

    27 publications

    4.8K citations

  4. University of Pittsburgh

    Pittsburgh, United States

    7 h-index

    64 publications

    7.8K citations

  5. University of Pennsylvania

    Philadelphia, United States

    6 h-index

    15 publications

    1.2K citations

  6. National Institutes of Health

    Bethesda, United States

    6 h-index

    44 publications

    7.5K citations

  7. Cincinnati Children's Hospital Medical Center

    Cincinnati, United States

    5 h-index

    12 publications

    678 citations

  8. Centre for Human Genetics

    Oxford, United Kingdom

    5 h-index

    28 publications

    804 citations

1–8 of 211

Venues

  1. Development

    18 publications · 2.9K citations

    16

    h-index

  2. Developmental Biology

    9 publications · 551 citations

    9

    h-index

  3. Developmental Dynamics

    8 publications · 232 citations

    8

    h-index

  4. Human Molecular Genetics

    6 publications · 517 citations

    6

    h-index

  5. PLoS ONE

    5 publications · 157 citations

    5

    h-index

1–5