Concepedia

Lead Antibody Identification

Lead Antibody Identification is a systematic process in antibody discovery that constitutes the critical stage wherein candidate antibodies are evaluated and prioritized based on specific functional and biophysical criteria to select the most promising variant for therapeutic development.

12

Publications

506

Citations

145

Authors

28

Institutions

Publications per year

2017–2026

8

Parents

Publications

12

Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody

Sanjaya Singh, Rachel Kroe‐Barrett, Keith A. Canada et al. · mAbs · 2015 · 122 citations · Full text

, , +17

High throughput solution-based measurement of antibody-antigen affinity and epitope binning

Patricia A. Estep, Felicia Reid, Claire Nauman et al. · mAbs · 2013 · 78 citations · Full text

, , +17

Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease

Michael X. Henderson, Dustin J. Covell, Charlotte Hiu-Yan Chung et al. · Neurobiology of Disease · 2019 · 47 citations · Full text

, , +17

Development of Siglec-9 Blocking Antibody to Enhance Anti-Tumor Immunity

Hyeree Choi, Michelle Ho, Opeyemi S. Adeniji et al. · Frontiers in Oncology · 2021 · 46 citations · Full text

, , +17

Rapid charge variant analysis of monoclonal antibodies to support lead candidate biopharmaceutical development

Anne Trappe, Florian Füssl, Sara Carillo et al. · Journal of Chromatography B · 2018 · 41 citations

, , +16

1–5 of 12

Authors

145

  1. JQ
    John Q. Trojanowski

    University of Pennsylvania, United States

    1 publications · 47 citations

    1

    h-index

  2. HG
    Haibing Guo

    Hubei University of Science and Technology, China

    1 publications · 19 citations

    1

    h-index

  3. GG
    Ge Gao

    Chinese Academy of Sciences, China

    1 publications · 19 citations

    1

    h-index

  4. ME
    Miles Eckley

    Colorado State University, United States

    1 publications · 38 citations

    1

    h-index

  5. DK
    Dilip K. Challa

    The University of Texas Southwestern Medical Center, United States

    1 publications · 38 citations

    1

    h-index

1–5 of 145

Institutions

28

  1. Adimab (United States)

    Lebanon, United States

    1 h-index

    7 publications

    546 citations

  2. University of Georgia

    Athens, United States

    1 h-index

    3 publications

    99 citations

  3. Dublin City University

    Dublin, Ireland

    1 h-index

    2 publications

    82 citations

  4. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    1 h-index

    2 publications

    42 citations

  5. Wuhan Institute of Virology

    Wuhan, China

    1 h-index

    15 publications

    285 citations

  6. Institute for Protein Innovation

    Boston, United States

    1 h-index

    1 publications

    21 citations

  7. Chinese Academy of Sciences

    Beijing, China

    1 h-index

    15 publications

    285 citations

  8. Colorado State University

    Fort Collins, United States

    1 h-index

    8 publications

    304 citations

1–8 of 28

Venues

  1. mAbs

    5 publications · 268 citations

    5

    h-index

  2. Cold Spring Harbor Protocols

    1 publications · 20 citations

    1

    h-index

  3. Journal of Chromatography B

    1 publications · 41 citations

    1

    h-index

  4. Neurobiology of Disease

    1 publications · 47 citations

    1

    h-index

  5. Frontiers in Immunology

    1 publications · 38 citations

    1

    h-index

1–5