Concepedia

Itch Interactions

Itch Interactions is a theoretical construct in itch neuroscience that characterizes the dynamic, bidirectional modulations between pruriceptive signaling pathways and co-localized sensory mechanisms—such as pain, touch, or inflammation—as they jointly influence the generation, transmission, and perception of itch within the central and peripheral nervous systems.

8

Publications

578

Citations

51

Authors

22

Institutions

Publications per year

2017–2026

1

Parents

Publications

8

Cowhage-Evoked Itch Is Mediated by a Novel Cysteine Protease: A Ligand of Protease-Activated Receptors

Vemuri B. Reddy, Aurel O. Iuga, Steve G. Shimada et al. · Journal of Neuroscience · 2008 · 252 citations · Full text

, , +13

The Ubiquitin Ligase Itch Is Auto-ubiquitylated in Vivo and in Vitro but Is Protected from Degradation by Interacting with the Deubiquitylating Enzyme FAM/USP9X

Rania Mouchantaf, Bilal Azakir, Peter S. McPherson et al. · Journal of Biological Chemistry · 2006 · 118 citations · Full text

, , +15

Itch genetically interacts with Notch1 in a mouse autoimmune disease model

Lydia E. Matesic, Diana C. Haines, Neal G. Copeland et al. · Human Molecular Genetics · 2006 · 49 citations · Full text

, , +16

Itch, an E3 ligase of Oct4, is required for embryonic stem cell self‐renewal and pluripotency induction

Bing Liao, Xiaoming Zhong, Huiming Xu et al. · Journal of Cellular Physiology · 2012 · 49 citations

, , +14

Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer

Zhu-lin Luo, Huijun Luo, Fang Chen et al. · Oncotarget · 2015 · 36 citations · Full text

, , +17

1–5 of 8

Authors

51

  1. VB
    Vemuri B. Reddy

    Massachusetts General Hospital, United States

    1 publications · 252 citations

    1

    h-index

  2. HL
    Huijun Luo

    Mayo Clinic in Arizona, United States

    1 publications · 36 citations

    1

    h-index

  3. BL
    Bing Liao

    Shanghai Jiao Tong University, China

    1 publications · 49 citations

    1

    h-index

  4. SM
    Susan Millard

    The University of Queensland, Australia

    1 publications · 118 citations

    1

    h-index

  5. TW
    Tao Wang

    Air Force Medical University, China

    1 publications · 36 citations

    1

    h-index

1–5 of 51

Institutions

22

  1. McGill University

    Montreal, Canada

    1 h-index

    1 publications

    118 citations

  2. Women's & Children's Health Research Institute

    North Adelaide, Australia

    1 h-index

    2 publications

    236 citations

  3. University of Chicago

    Chicago, United States

    1 h-index

    2 publications

    98 citations

  4. Shanghai Jiao Tong University

    Shanghai, China

    1 h-index

    7 publications

    343 citations

  5. National Institute of Environmental Health Sciences

    Durham, United States

    1 h-index

    4 publications

    108 citations

  6. Frederick National Laboratory for Cancer Research

    Frederick, United States

    1 h-index

    1 publications

    49 citations

  7. Massachusetts General Hospital

    Boston, United States

    1 h-index

    3 publications

    756 citations

  8. Yale University

    New Haven, United States

    1 h-index

    2 publications

    504 citations

1–8 of 22

Venues

  1. Virology Journal

    1 publications · 28 citations

    1

    h-index

  2. Toxicon

    1 publications · 19 citations

    1

    h-index

  3. Journal of Biological Chemistry

    JBC · 1 publications · 118 citations

    1

    h-index

  4. Human Molecular Genetics

    1 publications · 49 citations

    1

    h-index

  5. Journal of Cellular Physiology

    1 publications · 49 citations

    1

    h-index

1–5