Concepedia

Intermediate Metabolite Control

Intermediate Metabolite Control is a regulatory mechanism in metabolic pathway integration that modulates flux through metabolic networks by altering the concentration or activity of intermediate metabolites, thereby influencing the rate and direction of biochemical reactions.

11

Publications

869

Citations

48

Authors

23

Institutions

Publications per year

2017–2026

4

Parents

Publications

11

Sequential control of biosynthetic pathways for balanced utilization of metabolic intermediates in Saccharomyces cerevisiae

Wenping Xie, Lidan Ye, Xiaomei Lv et al. · Metabolic Engineering · 2014 · 212 citations

, , +16

A ‘top‐down’ approach to the determination of control coefficients in metabolic control theory

Guy C. Brown, Roderick P. Hafner, Martin D. Brand · European Journal of Biochemistry · 1990 · 209 citations · Full text

, , +14

The regulatory significance of intermediary metabolites: Control of aromatic acid biosynthesis by feedback inhibition in Bacillus subtilis

Roy A. Jensen, Eugene W. Nester · Journal of Molecular Biology · 1965 · 95 citations

, , +17

Yeast AMP Pathway Genes Respond to Adenine through Regulated Synthesis of a Metabolic Intermediate

Karine Rébora, Christine Desmoucelles, Françoise Borne et al. · Molecular and Cellular Biology · 2001 · 95 citations · Full text

, , +15

Regulatory architecture determines optimal regulation of gene expression in metabolic pathways

Victor Chubukov, Ignacio A. Zuleta, Hao Li · Proceedings of the National Academy of Sciences · 2012 · 68 citations · Full text

, , +15

1–5 of 11

Authors

48

  1. VC
    Victor Chubukov

    Agios Pharmaceuticals (United States), United States

    2 publications · 118 citations

    2

    h-index

  2. FW
    Fangli Wu

    Shanghai Ocean University, China

    1 publications · 32 citations

    1

    h-index

  3. CC
    Chen-Shan Chin

    Pacific Biosciences (United States), United States

    1 publications · 50 citations

    1

    h-index

  4. CD
    Christine Desmoucelles

    Centre National de la Recherche Scientifique, France

    1 publications · 95 citations

    1

    h-index

  5. TS
    Takashi Shimazu

    Ehime University, Japan

    1 publications · 37 citations

    1

    h-index

1–5 of 48

Institutions

23

  1. University of California, Berkeley

    Berkeley, United States

    2 h-index

    4 publications

    236 citations

  2. University of California, San Francisco

    San Francisco, United States

    2 h-index

    8 publications

    454 citations

  3. Leibniz Institute for Baltic Sea Research Warnemünde

    Warnemünde, Germany

    1 h-index

    1 publications

    32 citations

  4. Ministry of Education

    Wellington, New Zealand

    1 h-index

    1 publications

    212 citations

  5. University of Rostock

    Rostock, Germany

    1 h-index

    6 publications

    192 citations

  6. Zhejiang University

    Hangzhou, China

    1 h-index

    5 publications

    1.1K citations

  7. Novo Nordisk Foundation

    Copenhagen, Denmark

    1 h-index

    2 publications

    48 citations

  8. Chongqing Medical University

    Chongqing, China

    1 h-index

    2 publications

    74 citations

1–8 of 23

Venues

  1. Metabolic Engineering

    1 publications · 212 citations

    1

    h-index

  2. Neuroendocrinology

    1 publications · 37 citations

    1

    h-index

  3. The Science of The Total Environment

    1 publications · 32 citations

    1

    h-index

  4. Journal of Molecular Biology

    JMB · 1 publications · 95 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 68 citations

    1

    h-index

1–5