Concepedia

Intermediate Clinical Endpoints

Intermediate Clinical Endpoints is a type of clinical outcome measure that serves as a surrogate marker of a disease process, enabling earlier assessment of treatment effects during the accelerated approval of medical therapies by predicting meaningful patient benefits with reasonable likelihood.

129

Publications

11.1K

Citations

945

Authors

456

Institutions

Publications per year

2017–2026

34

Variants

Intermediate Clinical Endpoint

Parents

Publications

129

Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium

M.B. Leon, Nicolò Piazza, Eugenia Nikolsky et al. · European Heart Journal · 2011 · 1.2K citations · Full text

, , +17

Short-term Intravenous Milrinone for Acute Exacerbation of Chronic Heart Failure<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

Michael S. Cuffe · JAMA · 2002 · 1.2K citations

, , +17

Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document†

A. Pieter Kappetein, Stuart J. Head, Philippe Généreux et al. · European Heart Journal · 2012 · 1K citations · Full text

, , +17

Standardized Endpoint Definitions for Transcatheter Aortic Valve Implantation Clinical Trials

Martin B. Leon, Nicolò Piazza, Eugenia Nikolsky et al. · Journal of the American College of Cardiology · 2011 · 734 citations

, , +17

Statistical validation of intermediate endpoints for chronic diseases

Laurence S. Freedman, Barry I. Graubard, Arthur Schatzkin · Statistics in Medicine · 1992 · 655 citations

, , +15

1–5 of 129

Authors

945

  1. PW
    Patrick W. Serruys

    Erasmus University Rotterdam, Netherlands

    5 publications · 3.5K citations

    5

    h-index

  2. EH
    Eugene H. Blackstone

    Cleveland Clinic, United States

    5 publications · 3.5K citations

    5

    h-index

  3. DE
    Donald E. Cutlip

    Beth Israel Deaconess Medical Center, United States

    5 publications · 3.5K citations

    5

    h-index

  4. SW
    Stephan Windecker

    University Hospital of Bern, Switzerland

    4 publications · 3.4K citations

    4

    h-index

  5. PV
    Pascal Vranckx

    Hartcentrum Hasselt, Belgium

    4 publications · 3.4K citations

    4

    h-index

1–5 of 945

Institutions

456

  1. Harvard University

    Cambridge, United States

    10 h-index

    22 publications

    776 citations

  2. National Cancer Institute

    Bethesda, United States

    6 h-index

    17 publications

    2.9K citations

  3. University of California, San Francisco

    San Francisco, United States

    6 h-index

    8 publications

    276 citations

  4. Duke University

    Durham, United States

    6 h-index

    7 publications

    1.4K citations

  5. University of Minnesota

    Minneapolis, United States

    5 h-index

    5 publications

    492 citations

  6. Johns Hopkins University

    Baltimore, United States

    5 h-index

    7 publications

    274 citations

  7. Massachusetts General Hospital

    Boston, United States

    5 h-index

    8 publications

    333 citations

  8. Erasmus MC

    Rotterdam, The Netherlands

    4 h-index

    46 publications

    33K citations

1–8 of 456

Venues

  1. PubMed

    Repository · 8 publications · 252 citations

    8

    h-index

  2. The Annals of Thoracic Surgery

    ATS · 4 publications · 111 citations

    4

    h-index

  3. European Heart Journal

    4 publications · 2.3K citations

    4

    h-index

  4. Blood

    3 publications · 186 citations

    3

    h-index

  5. Urology

    3 publications · 84 citations

    3

    h-index

1–5