Concepedia

Interlocking Feedback Loops

Interlocking Feedback Loops is a regulatory architecture within circadian clock mechanisms that consists of multiple transcriptional-translational feedback loops interconnected such that components of one loop serve as regulators of another, thereby generating robust and precise rhythmicity through mutual stabilization and phase coordination.

14

Publications

1.7K

Citations

54

Authors

30

Institutions

Publications per year

2017–2026

2

Parents

Publications

14

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

Andrew C. Liu, Hien Tran, Eric Erquan Zhang et al. · PLoS Genetics · 2008 · 407 citations · Full text

, , +15

Interlocked Feedback Loops Within the <i>Drosophila</i> Circadian Oscillator

Nick R. J. Glossop, Lisa C. Lyons, Paul E. Hardin · Science · 1999 · 376 citations

, , +16

Interlocked feedback loops contribute to the robustness of the <i>Neurospora</i> circadian clock

Ping Cheng, Yuhong Yang, Yi Liu · Proceedings of the National Academy of Sciences · 2001 · 251 citations · Full text

, , +15

Modeling Circadian Oscillations with Interlocking Positive and Negative Feedback Loops

Paul Smolen, Douglas A. Baxter, John H. Byrne · Journal of Neuroscience · 2001 · 240 citations · Full text

, , +16

Robust Oscillations within the Interlocked Feedback Model of Drosophila Circadian Rhythm

Hiroki R. Ueda, Masatoshi Hagiwara, Hiroaki Kitano · Journal of Theoretical Biology · 2001 · 166 citations

, , +16

1–5 of 14

Authors

54

  1. ZQ
    Zhipeng Qu

    The University of Adelaide, Australia

    1 publications · 30 citations

    1

    h-index

  2. TS
    Treenut Saithong

    King Mongkut's University of Technology Thonburi, Thailand

    1 publications · 22 citations

    1

    h-index

  3. TD
    Timothy D. Ludwig

    Appalachian State University, United States

    1 publications · 27 citations

    1

    h-index

  4. PL
    Pietro Laneve

    Sapienza University of Rome, Italy

    1 publications · 19 citations

    1

    h-index

  5. ZX
    Zhi Xie

    Sun Yat-sen University, China

    1 publications · 40 citations

    1

    h-index

1–5 of 54

Institutions

30

  1. The University of Tokyo

    Tokyo, Japan

    2 h-index

    4 publications

    223 citations

  2. Mongolian Academy of Sciences

    Ulaanbaatar, Mongolia

    1 h-index

    1 publications

    10 citations

  3. University of California San Diego

    San Diego, United States

    1 h-index

    6 publications

    2.4K citations

  4. The University of Texas Health Science Center at Houston

    Houston, United States

    1 h-index

    3 publications

    720 citations

  5. Model Animal Research Center

    Nanjing, China

    1 h-index

    9 publications

    270 citations

  6. Fudan University

    Shanghai, China

    1 h-index

    1 publications

    30 citations

  7. Appalachian State University

    Boone, United States

    1 h-index

    2 publications

    54 citations

  8. Sony Computer Science Laboratories

    Tokyo, Japan

    1 h-index

    1 publications

    166 citations

1–8 of 30

Venues

  1. Journal of Theoretical Biology

    3 publications · 248 citations

    3

    h-index

  2. Materials Research Bulletin

    1 publications · 21 citations

    1

    h-index

  3. Biophysical Journal

    1 publications · 10 citations

    1

    h-index

  4. Mathematical Biosciences

    1 publications · 19 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 251 citations

    1

    h-index

1–5