Concepedia

Interface Hotspot Prediction

Interface Hotspot Prediction is a computational method within the field of protein structure analysis that identifies specific residues at protein-protein interaction interfaces whose energetic contributions are critical for binding stability and specificity.

87

Publications

6K

Citations

324

Authors

146

Institutions

Publications per year

2017–2026

28

Parents

Publications

87

Computational Alanine Scanning of Protein-Protein Interfaces

Tanja Kortemme, David E. Kim, David Baker · Science s STKE · 2004 · 612 citations

, , +16

Identification of computational hot spots in protein interfaces: combining solvent accessibility and inter-residue potentials improves the accuracy

Nurcan Tunçbağ, Attila Gürsoy, Özlem Keskin · Bioinformatics · 2009 · 265 citations · Full text

, , +13

KFC2: A knowledge‐based hot spot prediction method based on interface solvation, atomic density, and plasticity features

Xiaolei Zhu, Julie C. Mitchell · Proteins Structure Function and Bioinformatics · 2011 · 242 citations

, , +16

An automated decision‐tree approach to predicting protein interaction hot spots

Steven J. Darnell, David Page, Julie C. Mitchell · Proteins Structure Function and Bioinformatics · 2007 · 219 citations

, , +17

APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility

Junfeng Xia, Xing-Ming Zhao, Jiangning Song et al. · BMC Bioinformatics · 2010 · 212 citations · Full text

, , +14

1–5 of 87

Authors

324

  1. LD
    Lei Deng

    Central South University, China

    6 publications · 371 citations

    6

    h-index

  2. IS
    Irina S. Moreira

    Universidade do Porto, Portugal

    5 publications · 243 citations

    5

    h-index

  3. JL
    Jinyan Li

    University of Technology Sydney, Australia

    4 publications · 133 citations

    4

    h-index

  4. JX
    Junfeng Xia

    Anhui University, China

    4 publications · 315 citations

    4

    h-index

  5. PC
    Peng Chen

    Anhui University, China

    4 publications · 239 citations

    4

    h-index

1–5 of 324

Institutions

146

  1. Anhui University

    Hefei, China

    7 h-index

    28 publications

    1.1K citations

  2. Central South University

    Changsha, China

    5 h-index

    12 publications

    932 citations

  3. Universidade do Porto

    Porto, Portugal

    5 h-index

    16 publications

    803 citations

  4. Fudan University

    Shanghai, China

    5 h-index

    6 publications

    336 citations

  5. University of Leeds

    Leeds, United Kingdom

    4 h-index

    22 publications

    1.4K citations

  6. Rede de Química e Tecnologia

    Porto, Portugal

    4 h-index

    14 publications

    640 citations

  7. Tongji University

    Shanghai, China

    4 h-index

    12 publications

    462 citations

  8. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    4 h-index

    15 publications

    1.1K citations

1–8 of 146

Venues

  1. Nucleic Acids Research

    8 publications · 867 citations

    8

    h-index

  2. BMC Bioinformatics

    8 publications · 630 citations

    8

    h-index

  3. Proteins Structure Function and Bioinformatics

    8 publications · 652 citations

    8

    h-index

  4. Journal of Chemical Information and Modeling

    JCIM · 6 publications · 293 citations

    6

    h-index

  5. PLoS ONE

    5 publications · 199 citations

    5

    h-index

1–5