Concepedia

Inter-species Extrapolation

Inter-Species Extrapolation is a pharmacological inference method that generalizes drug response data from one species to another by accounting for interspecific differences in pharmacodynamics, thereby enabling the prediction of drug effects in humans based on nonclinical studies.

44

Publications

2.4K

Citations

189

Authors

104

Institutions

Publications per year

2017–2026

7

Parents

Publications

44

Rodent Brain Growth Stages: An Analytical Review

Alberto Gottlieb, I.K. Keydar, Herman T. Epstein · Biology of the Neonate · 2009 · 185 citations

, , +17

Biological basis for extrapolation across mammalian species

I. W. F. Davidson, Jean Parker, Robert P. Beliles · Regulatory Toxicology and Pharmacology · 1986 · 160 citations

, , +6

Editor’s Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity

Carlie A. LaLone, Daniel L. Villeneuve, David Lyons et al. · Toxicological Sciences · 2016 · 158 citations

, , +17

Quantitative Cross-Species Extrapolation between Humans and Fish: The Case of the Anti-Depressant Fluoxetine

Luigi Margiotta‐Casaluci, Stewart F. Owen, Rob I. Cumming et al. · PLoS ONE · 2014 · 135 citations · Full text

, , +14

Cross-species extrapolation of chronic nickel Biotic Ligand Models

Christian E. Schlekat, Eric van Genderen, Karel De Schamphelaere et al. · The Science of The Total Environment · 2010 · 112 citations

, , +10

1–5 of 44

Authors

189

  1. CA
    Carlie A. LaLone

    Environmental Protection Agency, United States

    6 publications · 421 citations

    6

    h-index

  2. DL
    Daniel L. Villeneuve

    Environmental Protection Agency, United States

    3 publications · 337 citations

    3

    h-index

  3. GT
    Gerald T. Ankley

    Environmental Protection Agency, United States

    3 publications · 337 citations

    3

    h-index

  4. HW
    Henry W. Helgen

    Environmental Protection Agency, United States

    2 publications · 267 citations

    2

    h-index

  5. TR
    Thomas R. Transue

    Environmental Protection Agency, United States

    2 publications · 90 citations

    2

    h-index

1–5 of 189

Institutions

104

  1. Environmental Protection Agency

    Washington, United States

    11 h-index

    41 publications

    3.1K citations

  2. Research Triangle Park Foundation

    Durham, United States

    5 h-index

    11 publications

    532 citations

  3. National Academies of Sciences, Engineering, and Medicine

    Washington, United States

    3 h-index

    3 publications

    210 citations

  4. RWTH Aachen University

    Aachen, Germany

    2 h-index

    3 publications

    284 citations

  5. University of Bedfordshire

    Luton, United Kingdom

    2 h-index

    6 publications

    128 citations

  6. Syngenta (United Kingdom)

    Fulbourn, United Kingdom

    2 h-index

    2 publications

    119 citations

  7. University of Florida

    Gainesville, United States

    2 h-index

    2 publications

    110 citations

  8. Stockholm University

    Stockholm, Sweden

    2 h-index

    4 publications

    134 citations

1–8 of 104

Venues

  1. Environmental Toxicology and Chemistry

    5 publications · 208 citations

    5

    h-index

  2. Environmental Science & Technology

    4 publications · 248 citations

    4

    h-index

  3. Toxicological Sciences

    3 publications · 217 citations

    3

    h-index

  4. PubMed

    Repository · 3 publications · 43 citations

    3

    h-index

  5. PLoS ONE

    2 publications · 159 citations

    2

    h-index

1–5