Concepedia

Integrin-mediated Motility

Integrin-Mediated Motility is a cellular motility mechanism characterized by the engagement of integrin receptors to mediate adhesion between the cell and the extracellular matrix, thereby enabling force transduction and directional movement through focal adhesion dynamics and cytoskeletal reorganization.

246

Publications

23.2K

Citations

1.3K

Authors

390

Institutions

Publications per year

2017–2026

30

Parents

Publications

246

Cell adhesion and motility depend on nanoscale RGD clustering

Gargi Maheshwari, Gillian Brown, Douglas A. Lauffenburger et al. · Journal of Cell Science · 2000 · 941 citations

, , +17

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

Patricia J. Keely, John Westwick, Ian P. Whitehead et al. · Nature · 1997 · 731 citations

, , +12

Mechanically Activated Integrin Switch Controls α <sub>5</sub> β <sub>1</sub> Function

Julie C. Friedland, Mark H. Lee, David Boettiger · Science · 2009 · 710 citations

, , +17

The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro.

Lucy Liaw, Michael P. Skinner, Elaine W. Raines et al. · Journal of Clinical Investigation · 1995 · 510 citations · Full text

, , +16

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

Herbert B. Schiller, Michaela-Rosemarie Hermann, Julien Polleux et al. · Nature Cell Biology · 2013 · 424 citations

, , +17

1–5 of 246

Authors

1.3K

  1. AF
    Alan F. Horwitz

    University of Virginia, United States

    5 publications · 1.2K citations

    5

    h-index

  2. DA
    Douglas A. Lauffenburger

    Massachusetts Institute of Technology, United States

    4 publications · 1.8K citations

    4

    h-index

  3. PJ
    Peter J. Parker

    The Honourable Society of Lincoln's Inn, United Kingdom

    3 publications · 689 citations

    3

    h-index

  4. JI
    Johanna Ivaska

    University of Turku, Finland

    3 publications · 472 citations

    3

    h-index

  5. CW
    Chuanyue Wu

    University of Pittsburgh, United States

    3 publications · 468 citations

    3

    h-index

1–5 of 1.3K

Institutions

390

  1. Inserm

    Paris, France

    11 h-index

    41 publications

    2.2K citations

  2. Scripps Research Institute

    San Diego, United States

    8 h-index

    22 publications

    3.3K citations

  3. University of Illinois Urbana-Champaign

    Urbana, United States

    8 h-index

    31 publications

    5.4K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    38 publications

    2.9K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    7 h-index

    27 publications

    6.5K citations

  6. University of Utah

    Salt Lake City, United States

    6 h-index

    15 publications

    1K citations

  7. University of California, San Francisco

    San Francisco, United States

    6 h-index

    23 publications

    2.5K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    10 publications

    5.9K citations

1–8 of 390

Venues

  1. Journal of Biological Chemistry

    JBC · 29 publications · 2.9K citations

    26

    h-index

  2. Journal of Cell Science

    18 publications · 2.4K citations

    18

    h-index

  3. The Journal of Cell Biology

    JCB · 17 publications · 2.5K citations

    16

    h-index

  4. Experimental Cell Research

    ECR · 8 publications · 535 citations

    8

    h-index

  5. PubMed

    Repository · 8 publications · 964 citations

    8

    h-index

1–5