Concepedia

Integrin-mediated Colonization

Integrin-Mediated Colonization is a biological mechanism within the process of metastatic colonization whereby circulating tumor cells establish secondary tumors in distant organs through the specific activation of integrin-dependent signaling pathways that facilitate adhesion, survival, and proliferation in the foreign microenvironment.

51

Publications

3.3K

Citations

361

Authors

130

Institutions

Publications per year

2017–2026

7

Parents

Publications

51

Fetal and Adult Hematopoietic Stem Cells Require β1 Integrin Function for Colonizing Fetal Liver, Spleen, and Bone Marrow

Alexandre J. Potocnik, Cord Brakebusch, Reinhard Fässler · Immunity · 2000 · 388 citations · Full text

, , +14

An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization

Tsukasa Shibue, Mary W. Brooks, Robert A. Weinberg · Cancer Cell · 2013 · 205 citations · Full text

, , +17

Integrin-mediated localization of Bordetella pertussis within macrophages: role in pulmonary colonization.

Kapo Saukkonen, Carmen Cabellos, Margaret Burroughs et al. · The Journal of Experimental Medicine · 1991 · 195 citations · Full text

, , +16

Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade

Michelle B. Chen, John M. Lamar, Ran Li et al. · Cancer Research · 2016 · 164 citations · Full text

, , +17

Integrin α4β1 Promotes Monocyte Trafficking and Angiogenesis in Tumors

Hui Jin, Jingmei Su, Barbara Garmy‐Susini et al. · Cancer Research · 2006 · 128 citations

, , +17

1–5 of 51

Authors

361

  1. JM
    John M. Lamar

    Albany Medical Center Hospital, United States

    2 publications · 194 citations

    2

    h-index

  2. MD
    Michael D. Henry

    University of Iowa, United States

    2 publications · 127 citations

    2

    h-index

  3. DL
    Donna L. Livant

    University of Michigan, United States

    2 publications · 59 citations

    2

    h-index

  4. CR
    Christof R. Hauck

    University of Konstanz, Germany

    2 publications · 171 citations

    2

    h-index

  5. CS
    Christopher S. Stipp

    University of Iowa, United States

    2 publications · 127 citations

    2

    h-index

1–5 of 361

Institutions

130

  1. Wayne State University

    Detroit, United States

    3 h-index

    16 publications

    660 citations

  2. Mario Negri Institute for Pharmacological Research

    Milan, Italy

    2 h-index

    2 publications

    171 citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    4 publications

    194 citations

  4. Helmholtz Centre for Infection Research

    Braunschweig, Germany

    2 h-index

    2 publications

    198 citations

  5. University of Iowa

    Iowa City, United States

    2 h-index

    16 publications

    1.1K citations

  6. University of California San Diego

    San Diego, United States

    2 h-index

    11 publications

    1K citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    6 publications

    1K citations

  8. University of Würzburg

    Würzburg, Germany

    2 h-index

    7 publications

    715 citations

1–8 of 130

Venues

  1. International Journal of Cancer

    5 publications · 210 citations

    5

    h-index

  2. Journal of Cell Science

    3 publications · 266 citations

    3

    h-index

  3. Molecular Cancer Research

    MCR · 3 publications · 136 citations

    3

    h-index

  4. Clinical & Experimental Metastasis

    3 publications · 107 citations

    3

    h-index

  5. Cancer Research

    2 publications · 292 citations

    2

    h-index

1–5