Concepedia

Intact Mass Profiling

Intact Mass Profiling is an analytical strategy in top-down proteomics that refers to the comprehensive measurement and characterization of the intact molecular masses of proteins directly from biological samples, enabling the identification of proteoforms without prior proteolytic digestion.

93

Publications

5.6K

Citations

496

Authors

187

Institutions

Publications per year

2017–2026

41

Variants

Intact Protein Mass Profiling

Parents

Publications

93

Mapping intact protein isoforms in discovery mode using top-down proteomics

John C. Tran, Leonid Zamdborg, Dorothy R. Ahlf et al. · Nature · 2011 · 658 citations · Full text

, , +13

Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems

Evan Murray, Jaehun Cho, Daniel Goodwin et al. · Cell · 2015 · 510 citations · Full text

, , +10

Peer Reviewed: Top-Down Proteomics

Neil L. Kelleher · Analytical Chemistry · 2004 · 496 citations

, , +16

Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics

Julia M. Burkhart, Cornelia Schumbrutzki, Stefanie Wortelkamp et al. · Journal of Proteomics · 2011 · 304 citations

, , +14

Direct mass spectrometric analysis of intact proteins of the yeast large ribosomal subunit using capillary LC/FTICR

Sang‐Won Lee, Scott J. Berger, Suzana Martinović et al. · Proceedings of the National Academy of Sciences · 2002 · 183 citations · Full text

, , +16

1–5 of 93

Authors

496

  1. NL
    Neil L. Kelleher

    Northwestern University, United States

    8 publications · 1.5K citations

    8

    h-index

  2. LM
    Lloyd M. Smith

    University of Wisconsin–Madison, United States

    5 publications · 168 citations

    5

    h-index

  3. MR
    Michael R. Shortreed

    University of Wisconsin–Madison, United States

    5 publications · 168 citations

    5

    h-index

  4. JF
    John F. Kellie

    GlaxoSmithKline (United States), United States

    5 publications · 948 citations

    5

    h-index

  5. LP
    Ljiljana Paša‐Tolić

    Pacific Northwest National Laboratory, United States

    5 publications · 440 citations

    5

    h-index

1–5 of 496

Institutions

187

  1. University of Wisconsin–Madison

    Madison, United States

    7 h-index

    44 publications

    1.9K citations

  2. Northwestern University

    Evanston, United States

    5 h-index

    38 publications

    8.4K citations

  3. Pacific Northwest National Laboratory

    Richland, United States

    5 h-index

    31 publications

    3.1K citations

  4. University of Illinois Urbana-Champaign

    Urbana, United States

    4 h-index

    36 publications

    10.9K citations

  5. Regeneron (United States)

    Tarrytown, United States

    3 h-index

    17 publications

    791 citations

  6. Energy Center of Wisconsin

    Madison, United States

    3 h-index

    3 publications

    120 citations

  7. Center for Drug Evaluation and Research

    Silver Spring, United States

    2 h-index

    5 publications

    125 citations

  8. Technische Universität Berlin

    Berlin, Germany

    2 h-index

    5 publications

    163 citations

1–8 of 187

Venues

  1. Analytical Chemistry

    20 publications · 1.2K citations

    16

    h-index

  2. Journal of Proteome Research

    JPR · 14 publications · 705 citations

    14

    h-index

  3. PROTEOMICS

    8 publications · 344 citations

    8

    h-index

  4. Journal of the American Society for Mass Spectrometry

    JASMS · 6 publications · 205 citations

    6

    h-index

  5. Journal of Proteomics

    5 publications · 403 citations

    5

    h-index

1–5