Concepedia

Insulator Complexes

Insulator Complexes is a class of chromatin-associated protein assemblies that function as genomic boundary elements by blocking enhancer-promoter interactions or shielding genes from position effects, thereby maintaining independent regulatory domains within the genome.

56

Publications

6K

Citations

227

Authors

93

Institutions

Publications per year

2017–2026

12

Parents

Publications

56

Insulator dysfunction and oncogene activation in IDH mutant gliomas

William Flavahan, Yotam Drier, Brian B. Liau et al. · Nature · 2015 · 1.3K citations · Full text

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Gene Density, Transcription, and Insulators Contribute to the Partition of the Drosophila Genome into Physical Domains

Chunhui Hou, Li Li, Zhaohui Qin et al. · Molecular Cell · 2012 · 539 citations · Full text

, , +17

CTCF Tethers an Insulator to Subnuclear Sites, Suggesting Shared Insulator Mechanisms across Species

Timur Yusufzai, Hideaki Tagami, Yoshihiro Nakatani et al. · Molecular Cell · 2004 · 485 citations · Full text

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Insulator function and topological domain border strength scale with architectural protein occupancy

Kevin Van Bortle, Michael H. Nichols, Li Li et al. · Genome biology · 2014 · 313 citations · Full text

, , +17

Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

Tsuyoshi Mishiro, Ko Ishihara, Shinjiro Hino et al. · The EMBO Journal · 2009 · 197 citations · Full text

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1–5 of 56

Authors

227

  1. PG
    Pavel Georgiev

    Institute of Gene Biology, Russia

    10 publications · 397 citations

    10

    h-index

  2. VG
    Victor G. Corces

    Johns Hopkins University, United States

    6 publications · 1.1K citations

    6

    h-index

  3. TA
    Tsutomu Aoki

    Princeton University, United States

    5 publications · 158 citations

    5

    h-index

  4. PS
    Paul Schedl

    Princeton University, United States

    5 publications · 201 citations

    5

    h-index

  5. DW
    Daniel Wolle

    Princeton University, United States

    5 publications · 211 citations

    5

    h-index

1–5 of 227

Institutions

93

  1. Institute of Gene Biology

    Moscow, Russia

    14 h-index

    53 publications

    2K citations

  2. National Institutes of Health

    Bethesda, United States

    10 h-index

    34 publications

    3K citations

  3. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    9 h-index

    31 publications

    2.7K citations

  4. Emory University

    Atlanta, United States

    7 h-index

    34 publications

    6.4K citations

  5. Princeton University

    Princeton, United States

    6 h-index

    21 publications

    816 citations

  6. Russian Academy of Sciences

    Moscow, Russia

    4 h-index

    12 publications

    252 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    21 publications

    2.4K citations

  8. Justus-Liebig-Universität Gießen

    Giessen, Germany

    3 h-index

    19 publications

    2.6K citations

1–8 of 93

Venues

  1. The EMBO Journal

    7 publications · 1K citations

    7

    h-index

  2. PLoS ONE

    4 publications · 166 citations

    4

    h-index

  3. Nature Communications

    4 publications · 338 citations

    4

    h-index

  4. Molecular and Cellular Biology

    MCB · 4 publications · 265 citations

    4

    h-index

  5. Molecular Cell

    3 publications · 1.1K citations

    3

    h-index

1–5