Concepedia

Insertion Sequence-induced Mutagenesis

Insertion Sequence-Induced Mutagenesis is a genetic mutagenesis mechanism in which the insertion of a mobile DNA element, known as an Insertion Sequence, into a gene or regulatory region disrupts normal genomic function, thereby generating a heritable mutation.

48

Publications

4.1K

Citations

136

Authors

66

Institutions

Publications per year

2017–2026

1

Parents

Publications

48

Interposon mutagenesis of soil and water bacteria: a family of DNA fragments designed for in vitro insertional mutagenesis of Gram-negative bacteria

R. Fellay, Joachim Frey, Henry Krisch · Gene · 1987 · 691 citations

, , +14

Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency

Jerry Pelletier, Nahum Sonenberg · Cell · 1985 · 637 citations

, , +16

Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition

Nancy Kleckner, Russell K. Chan, Bik‐Kwoon Tye et al. · Journal of Molecular Biology · 1975 · 320 citations

, , +11

Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene

Kirk R. Thomas, Mario R. Capecchi · Nature · 1986 · 235 citations

, , +13

Single-stranded hexameric linkers: a system for in-phase insertion mutagenesis and protein engineering

Francis Barany · Gene · 1985 · 148 citations

, , +13

1–5 of 48

Authors

136

  1. VV
    Vladimir V. Kapitonov

    Genetic Information Research Institute, United States

    2 publications · 62 citations

    2

    h-index

  2. ND
    Niels de Wind

    Leiden University Medical Center, Netherlands

    2 publications · 106 citations

    2

    h-index

  3. AB
    Anton Berns

    The Netherlands Cancer Institute, Netherlands

    2 publications · 106 citations

    2

    h-index

  4. JJ
    Jerzy Jurka

    Genetic Information Research Institute, United States

    2 publications · 62 citations

    2

    h-index

  5. HK
    Henry Krisch

    Laboratoire de Microbiologie et Génétique Moléculaires, France

    2 publications · 767 citations

    2

    h-index

1–5 of 136

Institutions

66

  1. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    16 publications

    1K citations

  2. Inserm

    Paris, France

    3 h-index

    10 publications

    526 citations

  3. University of British Columbia

    Vancouver, Canada

    2 h-index

    6 publications

    494 citations

  4. Université Paris Cité

    Paris, France

    2 h-index

    4 publications

    437 citations

  5. Oncode Institute

    Utrecht, Netherlands

    2 h-index

    8 publications

    400 citations

  6. Genetic Information Research Institute

    Mountain View, United States

    2 h-index

    4 publications

    124 citations

  7. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    2 h-index

    8 publications

    400 citations

  8. University of Geneva

    Geneva, Switzerland

    2 h-index

    6 publications

    2.3K citations

1–8 of 66

Venues

  1. Gene

    6 publications · 1.2K citations

    6

    h-index

  2. Molecular and General Genetics MGG

    4 publications · 159 citations

    4

    h-index

  3. Journal of Molecular Biology

    JMB · 3 publications · 380 citations

    3

    h-index

  4. Cell

    3 publications · 882 citations

    3

    h-index

  5. Oncogene

    2 publications · 67 citations

    2

    h-index

1–5