Concepedia

Initiation Phase Of Coagulation

The "Initiation Phase of Coagulation" is a foundational stage in the coagulation cascade wherein tissue factor exposed at the site of vascular injury binds to circulating factor VIIa to form a complex that activates factors IX and X, thereby triggering thrombin generation through extrinsic tenase activity.

163

Publications

10.6K

Citations

577

Authors

229

Institutions

Publications per year

2017–2026

17

Parents

Publications

163

Platelet Activation and Blood Coagulation

Edouard M. Bevers, Theo Lindhout, Johan W. M. Heemskerk · Thrombosis and Haemostasis · 2002 · 576 citations

, , +17

The Structural Biology of Expression and Function of Tissue Factor

Thomas S. Edgington, Nigel Mackman, Korbinian Brand et al. · Thrombosis and Haemostasis · 1991 · 556 citations

, , +17

Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade

James H. Morrissey, Habib Fakhrai, Thomas S. Edgington · Cell · 1987 · 320 citations

, , +16

Activation of human factor IX (Christmas factor).

Richard G. Di Scipio, Kotoku Kurachi, Earl W. Davie · Journal of Clinical Investigation · 1978 · 258 citations · Full text

, , +14

Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

Jacky Chi Ki Ngo, Mingdong Huang, David A. Roth et al. · Structure · 2008 · 238 citations · Full text

, , +16

1–5 of 163

Authors

577

  1. KG
    Kenneth G. Mann

    University of Vermont, United States

    13 publications · 1K citations

    12

    h-index

  2. SB
    Saulius Butenas

    University of Vermont, United States

    8 publications · 555 citations

    8

    h-index

  3. YN
    Yale Nemerson

    Icahn School of Medicine at Mount Sinai, United States

    6 publications · 550 citations

    6

    h-index

  4. KE
    Kathleen E. Brummel‐Ziedins

    University of Vermont, United States

    5 publications · 272 citations

    5

    h-index

  5. TO
    Thomas Orfeo

    University of Vermont, United States

    5 publications · 296 citations

    5

    h-index

1–5 of 577

Institutions

229

  1. University of Vermont

    Burlington, United States

    12 h-index

    35 publications

    2.9K citations

  2. Scripps Research Institute

    San Diego, United States

    5 h-index

    17 publications

    3.9K citations

  3. Scripps Health

    San Diego, United States

    5 h-index

    15 publications

    1.3K citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    5 h-index

    12 publications

    807 citations

  5. University of California San Diego

    San Diego, United States

    5 h-index

    13 publications

    1K citations

  6. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    14 publications

    2.1K citations

  7. Scripps Clinic

    La Jolla, United States

    4 h-index

    12 publications

    1.3K citations

  8. Duke University

    Durham, United States

    4 h-index

    8 publications

    402 citations

1–8 of 229

Venues

  1. Blood

    20 publications · 1.4K citations

    17

    h-index

  2. Thrombosis and Haemostasis

    17 publications · 1.5K citations

    14

    h-index

  3. Journal of Biological Chemistry

    JBC · 14 publications · 1.1K citations

    13

    h-index

  4. PubMed

    Repository · 15 publications · 857 citations

    12

    h-index

  5. Thrombosis Research

    10 publications · 337 citations

    10

    h-index

1–5