Concepedia

Inflammatory Pathway Modeling

Inflammatory Pathway Modeling is a computational or theoretical framework that formally represents the molecular and cellular interactions underlying inflammatory responses within biological systems, distinguished by its specific focus on delineating the activation, regulation, and crosstalk of signaling pathways driving inflammation.

63

Publications

2.8K

Citations

345

Authors

144

Institutions

Publications per year

2017–2026

20

Parents

Publications

63

A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation

Angela Reynolds, Jonathan E. Rubin, Gilles Clermont et al. · Journal of Theoretical Biology · 2006 · 266 citations

, , +16

Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling

Toshiaki Nakano, Shunsuke Katsuki, Mingxian Chen et al. · Circulation · 2018 · 205 citations · Full text

, , +17

Transient IκB Kinase Activity Mediates Temporal NF-κB Dynamics in Response to a Wide Range of Tumor Necrosis Factor-α Doses

Raymond Cheong, Adriel Bergmann, Shannon L. Werner et al. · Journal of Biological Chemistry · 2005 · 138 citations · Full text

, , +17

TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin

Lee Swanson, Gajanan D. Katkar, Julian S. Tam et al. · Proceedings of the National Academy of Sciences · 2020 · 107 citations · Full text

, , +15

Modeling endotoxin-induced systemic inflammation using an indirect response approach

Panagiota T. Foteinou, S E Calvano, S. F. Lowry et al. · Mathematical Biosciences · 2008 · 89 citations · Full text

, , +14

1–5 of 63

Authors

345

  1. YV
    Yoram Vodovotz

    University of Pittsburgh, United States

    8 publications · 588 citations

    8

    h-index

  2. GA
    Gary An

    University of Chicago, United States

    5 publications · 172 citations

    5

    h-index

  3. GC
    Gilles Clermont

    University of Pittsburgh, United States

    6 publications · 508 citations

    5

    h-index

  4. JE
    Jonathan E. Rubin

    University of Pittsburgh, United States

    5 publications · 425 citations

    4

    h-index

  5. IP
    Ioannis P. Androulakis

    Rutgers, The State University of New Jersey, United States

    4 publications · 182 citations

    4

    h-index

1–5 of 345

Institutions

144

  1. University of Pittsburgh

    Pittsburgh, United States

    10 h-index

    63 publications

    4.2K citations

  2. McGowan Institute for Regenerative Medicine

    Pittsburgh, United States

    6 h-index

    23 publications

    1.1K citations

  3. University of California San Diego

    San Diego, United States

    4 h-index

    18 publications

    1.9K citations

  4. Rutgers, The State University of New Jersey

    New Brunswick, United States

    4 h-index

    12 publications

    568 citations

  5. Johnson University

    Knoxville, United States

    4 h-index

    9 publications

    377 citations

  6. University of Pittsburgh Medical Center

    Pittsburgh, United States

    3 h-index

    5 publications

    636 citations

  7. Heidelberg University

    Heidelberg, Germany

    3 h-index

    4 publications

    117 citations

  8. University of Chicago

    Chicago, United States

    3 h-index

    4 publications

    122 citations

1–8 of 144

Venues

  1. PLoS ONE

    8 publications · 300 citations

    8

    h-index

  2. Bulletin of Mathematical Biology

    3 publications · 116 citations

    3

    h-index

  3. Journal of Theoretical Biology

    3 publications · 346 citations

    3

    h-index

  4. Mathematical Biosciences

    2 publications · 111 citations

    2

    h-index

  5. Shock

    2 publications · 132 citations

    2

    h-index

1–5