Concepedia

Indirect Response Model Simulation

Indirect Response Model Simulation is a computational modeling technique that belongs to the class of pharmacodynamic simulation methods, distinguished by its explicit representation of drug effects through mechanisms that modulate the production or loss rates of biological response variables rather than directly altering the response itself.

58

Publications

2.6K

Citations

268

Authors

119

Institutions

Publications per year

2017–2026

7

Parents

Publications

58

Comparison of four basic models of indirect pharmacodynamic responses

Natalie Dayneka, Varun Garg, William J. Jusko · Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 811 citations

, , +14

Characterization of four basic models of indirect pharmacodynamic responses

Amarnath Sharma, William J. Jusko · Journal of Pharmacokinetics and Biopharmaceutics · 1996 · 122 citations

, , +14

Pharmacokinetics and concentration–effect relationship of adalimumab in rheumatoid arthritis

David Ternant, Émilie Ducourau, P. Fuzibet et al. · British Journal of Clinical Pharmacology · 2014 · 92 citations · Full text

, , +16

Simulation of the Decadal Permafrost Distribution on the Qinghai‐Tibet Plateau (China) over the Past 50 Years

Cheng Weiming, Zhou Chenghu, Xi Chen · Permafrost and Periglacial Processes · 2012 · 78 citations

, , +17

Indirect-response model for the time course of leukopenia with anticancer drugs*

Hironobu Minami, Yasutsuna Sasaki, Nagahiro Saijo et al. · Clinical Pharmacology & Therapeutics · 1998 · 76 citations

, , +16

1–5 of 58

Authors

268

  1. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    10 publications · 1.1K citations

    10

    h-index

  2. WK
    Wojciech Krzyżański

    University at Buffalo, State University of New York, United States

    9 publications · 348 citations

    9

    h-index

  3. LR
    Lucian Radu‐Radulescu

    VA Palo Alto Health Care System, United States

    2 publications · 110 citations

    2

    h-index

  4. MD
    Meindert Danhof

    Leiden University, Netherlands

    2 publications · 43 citations

    2

    h-index

  5. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    2 publications · 144 citations

    2

    h-index

1–5 of 268

Institutions

119

  1. University at Buffalo, State University of New York

    Buffalo, United States

    11 h-index

    31 publications

    3.7K citations

  2. Centre for Human Drug Research

    Leiden, The Netherlands

    3 h-index

    12 publications

    243 citations

  3. Pitié-Salpêtrière Hospital

    Paris, France

    3 h-index

    12 publications

    377 citations

  4. Sorbonne Université

    Paris, France

    3 h-index

    12 publications

    377 citations

  5. China Pharmaceutical University

    Nanjing, China

    2 h-index

    12 publications

    228 citations

  6. Erasmus University Rotterdam

    Rotterdam, The Netherlands

    2 h-index

    7 publications

    349 citations

  7. GlaxoSmithKline (Italy)

    Verona, Italy

    2 h-index

    6 publications

    139 citations

  8. University Hospital of Bern

    Bern, Switzerland

    2 h-index

    4 publications

    260 citations

1–8 of 119

Venues

  1. 6

    h-index

  2. 5

    h-index

  3. CPT Pharmacometrics & Systems Pharmacology

    PSP · 5 publications · 96 citations

    5

    h-index

  4. British Journal of Clinical Pharmacology

    BJCP · 4 publications · 162 citations

    4

    h-index

  5. The Journal of Clinical Pharmacology

    4 publications · 124 citations

    4

    h-index

1–5