Concepedia

Imputation-based Fine Mapping

Imputation-Based Fine Mapping is a statistical genetics method that leverages genotype imputation to refine the localization of causal variants within a region of interest by integrating imputed genotypes with association data to distinguish true risk variants from correlated non-causal variants.

39

Publications

5K

Citations

691

Authors

354

Institutions

Publications per year

2017–2026

23

Parents

Publications

39

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Anubha Mahajan, Daniel Taliun, Matthias Thurner et al. · Nature Genetics · 2018 · 1.9K citations · Full text

, , +16

Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses

Alison R. Barton, Maxwell A. Sherman, Ronen E. Mukamel et al. · Nature Genetics · 2021 · 358 citations · Full text

, , +17

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies

Clive Hoggart, John C. Whittaker, Maria De Iorio et al. · PLoS Genetics · 2008 · 344 citations · Full text

, , +16

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

Catherine C. Robertson, Jamie Inshaw, Suna Önengüt-Gümüşcü et al. · Nature Genetics · 2021 · 296 citations

, , +17

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

Omer Weissbrod, Masahiro Kanai, Huwenbo Shi et al. · Nature Genetics · 2022 · 281 citations · Full text

, , +14

1–5 of 39

Authors

691

  1. JI
    Jerome I. Rotter

    Harbor–UCLA Medical Center, United States

    4 publications · 2K citations

    4

    h-index

  2. GC
    Graham Casey

    University of Southern California, United States

    4 publications · 159 citations

    4

    h-index

  3. CA
    Christopher A. Haiman

    University of Southern California, United States

    4 publications · 159 citations

    4

    h-index

  4. PK
    Peter K. Gregersen

    Feinstein Institute for Medical Research, United States

    4 publications · 400 citations

    4

    h-index

  5. YO
    Yukinori Okada

    The University of Osaka, Japan

    4 publications · 541 citations

    4

    h-index

1–5 of 691

Institutions

354

  1. Broad Institute

    Cambridge, United States

    13 h-index

    70 publications

    11.7K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    61 publications

    9.3K citations

  3. Brigham and Women's Hospital

    Boston, United States

    10 h-index

    33 publications

    2.8K citations

  4. University of California, San Francisco

    San Francisco, United States

    8 h-index

    20 publications

    996 citations

  5. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    17 publications

    8.7K citations

  6. University of Southern California

    Los Angeles, United States

    6 h-index

    33 publications

    1.5K citations

  7. Imperial College London

    London, United Kingdom

    6 h-index

    15 publications

    9K citations

  8. Massachusetts General Hospital

    Boston, United States

    6 h-index

    29 publications

    5.6K citations

1–8 of 354

Venues

  1. Nature Genetics

    6 publications · 3K citations

    6

    h-index

  2. Human Molecular Genetics

    4 publications · 273 citations

    4

    h-index

  3. Annals of Human Genetics

    3 publications · 170 citations

    3

    h-index

  4. medRxiv

    Repository · 3 publications · 54 citations

    3

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 93 citations

    2

    h-index

1–5