Concepedia

Image-based Transcriptomics

Image-Based Transcriptomics is a spatial gene expression methodology that integrates high-resolution imaging with molecular profiling to localize and quantify transcript abundance within intact tissue sections, thereby preserving the spatial architecture of gene activity.

128

Publications

12.6K

Citations

840

Authors

308

Institutions

Publications per year

2017–2026

72

Parents

Publications

128

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+

Chee-Huat Linus Eng, Michael J. Lawson, Qian Zhu et al. · Nature · 2019 · 1.8K citations

, , +12

Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression

Chenglong Xia, Jean Fan, George Emanuel et al. · Proceedings of the National Academy of Sciences · 2019 · 827 citations · Full text

, , +16

High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging

Shanshan He, Ruchir Bhatt, Carl Brown et al. · Nature Biotechnology · 2022 · 778 citations

, , +17

Programmable in situ amplification for multiplexed imaging of mRNA expression

Harry M. T. Choi, Joann Y Chang, Le A. Trinh et al. · Nature Biotechnology · 2010 · 725 citations · Full text

, , +12

Decoding global gene expression programs in liver cancer by noninvasive imaging

Eran Segal, Claude B. Sirlin, Clara Ooi et al. · Nature Biotechnology · 2007 · 634 citations

, , +16

1–5 of 128

Authors

840

  1. JL
    Joakim Lundeberg

    KTH Royal Institute of Technology, Sweden

    6 publications · 470 citations

    6

    h-index

  2. XZ
    Xiaowei Zhuang

    Harvard University, United States

    4 publications · 1.2K citations

    4

    h-index

  3. LC
    Long Cai

    California Institute of Technology, United States

    4 publications · 2.3K citations

    4

    h-index

  4. JR
    Jeffrey R. Moffitt

    Harvard University, United States

    4 publications · 799 citations

    4

    h-index

  5. RM
    Reza Mirzazadeh

    Science for Life Laboratory, Sweden

    3 publications · 350 citations

    3

    h-index

1–5 of 840

Institutions

308

  1. Science for Life Laboratory

    Stockholm, Sweden

    11 h-index

    59 publications

    4.6K citations

  2. Harvard University

    Cambridge, United States

    9 h-index

    41 publications

    8.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    47 publications

    3.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    35 publications

    6.2K citations

  5. KTH Royal Institute of Technology

    Stockholm, Sweden

    8 h-index

    38 publications

    3.7K citations

  6. California Institute of Technology

    Pasadena, United States

    7 h-index

    37 publications

    20.9K citations

  7. Karolinska Institutet

    Stockholm, Sweden

    6 h-index

    34 publications

    2K citations

  8. Stockholm University

    Stockholm, Sweden

    6 h-index

    11 publications

    663 citations

1–8 of 308

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 15 publications · 301 citations

    12

    h-index

  2. Nature Biotechnology

    8 publications · 3.3K citations

    8

    h-index

  3. Nature Methods

    7 publications · 690 citations

    7

    h-index

  4. Bioinformatics

    6 publications · 185 citations

    6

    h-index

  5. Briefings in Bioinformatics

    5 publications · 398 citations

    5

    h-index

1–5