Concepedia

Hypoxia-driven Invasion

Hypoxia-Driven Invasion is a biological mechanism of local tumor invasion in oral cancer characterized by the infiltration of cancer cells into surrounding tissues as a direct response to hypoxic microenvironmental conditions that induce adaptive molecular and cellular changes promoting motility and extracellular matrix degradation.

426

Publications

27.3K

Citations

2.9K

Authors

763

Institutions

Publications per year

2017–2026

161

Parents

Publications

426

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

Hua Zhong, Angelo M. De Marzo, Erik Laughner et al. · PubMed · 1999 · 2.2K citations

, , +14

Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.

Balaji Krishnamachary, Shannon Berg-Dixon, Brian Kelly et al. · PubMed · 2003 · 630 citations

, , +17

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

Jung Eun Park, Hon Sen Tan, Arnab Datta et al. · Molecular & Cellular Proteomics · 2010 · 599 citations · Full text

, , +17

Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype

Ling Li, Chao Li, Shaoxin Wang et al. · Cancer Research · 2016 · 563 citations · Full text

, , +17

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

Ting Wang, Daniele M. Gilkes, Naoharu Takano et al. · Proceedings of the National Academy of Sciences · 2014 · 485 citations · Full text

, , +17

1–5 of 426

Authors

2.9K

  1. HO
    Hideya Onishi

    Kyushu University, Japan

    7 publications · 203 citations

    7

    h-index

  2. GL
    Gregg L. Semenza

    Johns Hopkins University, United States

    6 publications · 3.6K citations

    6

    h-index

  3. MK
    Mitsuo Katano

    Kyushu University, Japan

    5 publications · 178 citations

    5

    h-index

  4. JL
    Jianjun Lei

    South China Agricultural University, China

    5 publications · 438 citations

    5

    h-index

  5. RP
    Rićhard P. Hill

    Ontario Institute for Cancer Research, Canada

    4 publications · 213 citations

    4

    h-index

1–5 of 2.9K

Institutions

763

  1. First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

    18 h-index

    126 publications

    9.3K citations

  2. Xi'an Jiaotong University

    Xi'an, China

    11 h-index

    42 publications

    2.1K citations

  3. Johns Hopkins University

    Baltimore, United States

    11 h-index

    51 publications

    6.1K citations

  4. Air Force Medical University

    Xi'an, China

    9 h-index

    36 publications

    1.2K citations

  5. Johns Hopkins Medicine

    Baltimore, United States

    9 h-index

    34 publications

    4.9K citations

  6. Sun Yat-sen University

    Guangzhou, China

    9 h-index

    46 publications

    2.1K citations

  7. Kyushu University

    Fukuoka, Japan

    8 h-index

    47 publications

    1.4K citations

  8. Renji Hospital

    Shanghai, China

    7 h-index

    31 publications

    3.7K citations

1–8 of 763

Venues

  1. PubMed

    Repository · 23 publications · 3.5K citations

    16

    h-index

  2. International Journal of Oncology

    16 publications · 698 citations

    15

    h-index

  3. Cancer Research

    15 publications · 2.4K citations

    15

    h-index

  4. PLoS ONE

    14 publications · 699 citations

    12

    h-index

  5. Oncotarget

    12 publications · 515 citations

    12

    h-index

1–5