Concepedia

Hyper-ige Syndrome

Hyper-IgE Syndrome is a rare primary immunodeficiency disorder characterized by elevated serum IgE levels, recurrent staphylococcal skin abscesses, and chronic dermatitis, distinguished by its triad of immunologic dysfunction, skeletal abnormalities, and distinctive facial features.

345

Publications

22.9K

Citations

2.3K

Authors

755

Institutions

Publications per year

2017–2026

67

Parents

Publications

345

<i>STAT3</i> Mutations in the Hyper-IgE Syndrome

Steven M. Holland, Frank R. DeLeo, Houda Zghal Elloumi et al. · New England Journal of Medicine · 2007 · 1.2K citations · Full text

, , +13

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

Joshua D. Milner, Jason M. Brenchley, Arian Laurence et al. · Nature · 2008 · 1.1K citations · Full text

, , +14

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

Yoshiyuki Minegishi, Masako Saitō, Shigeru Tsuchiya et al. · Nature · 2007 · 1K citations

, , +13

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

Qutayba Hamid, May Azzawi, Redwan Moqbel et al. · Journal of Clinical Investigation · 1991 · 846 citations · Full text

, , +16

Hyper-IgE Syndrome with Recurrent Infections — An Autosomal Dominant Multisystem Disorder

Bodo Grimbacher, Steven M. Holland, John I. Gallin et al. · New England Journal of Medicine · 1999 · 795 citations · Full text

, , +17

1–5 of 345

Authors

2.3K

  1. SM
    Steven M. Holland

    National Institute of Allergy and Infectious Diseases, United States

    28 publications · 6.2K citations

    25

    h-index

  2. AF
    Alexandra F. Freeman

    National Institute of Allergy and Infectious Diseases, United States

    26 publications · 4.3K citations

    24

    h-index

  3. BG
    Bodo Grimbacher

    University Medical Center Freiburg, Germany

    18 publications · 4.9K citations

    15

    h-index

  4. JM
    Jennifer M. Puck

    University of California, San Francisco, United States

    12 publications · 4K citations

    12

    h-index

  5. ED
    Ellen D. Renner

    Ludwig-Maximilians-Universität München, Germany

    12 publications · 860 citations

    12

    h-index

1–5 of 2.3K

Institutions

755

  1. National Institutes of Health

    Bethesda, United States

    31 h-index

    165 publications

    28.4K citations

  2. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    31 h-index

    151 publications

    40.3K citations

  3. Ludwig-Maximilians-Universität München

    Munich, Germany

    16 h-index

    123 publications

    9.3K citations

  4. University College London

    London, United Kingdom

    14 h-index

    31 publications

    8.3K citations

  5. Boston Children's Hospital

    Boston, United States

    14 h-index

    47 publications

    3.4K citations

  6. Inserm

    Paris, France

    13 h-index

    109 publications

    12.9K citations

  7. University Medical Center Freiburg

    Freiburg im Breisgau, Germany

    12 h-index

    49 publications

    7.6K citations

  8. Harvard University

    Cambridge, United States

    12 h-index

    43 publications

    3.1K citations

1–8 of 755

Venues

  1. Journal of Allergy and Clinical Immunology

    29 publications · 3K citations

    25

    h-index

  2. PubMed

    Repository · 26 publications · 698 citations

    15

    h-index

  3. Journal of Clinical Immunology

    18 publications · 583 citations

    14

    h-index

  4. Annals of Allergy Asthma & Immunology

    ACAAI · 13 publications · 394 citations

    12

    h-index

  5. Clinical Immunology

    10 publications · 480 citations

    10

    h-index

1–5