Concepedia

Humanized Rat Models

Humanized Rat Model is a type of humanized animal model in which a rat is engrafted with human cells, tissues, or genes to recapitulate human physiology, disease mechanisms, or immune responses in a living organism.

110

Publications

5K

Citations

636

Authors

288

Institutions

Publications per year

2017–2026

28

Variants

Humanized Rat Model

Parents

Publications

110

WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited

Luke Boulter, Rachel V. Guest, Timothy J. Kendall et al. · Journal of Clinical Investigation · 2015 · 274 citations · Full text

, , +16

Comparison of five different rat models of peripheral nerve injury

Tom Dowdall, Ian Robinson, T. F. Meert · Pharmacology Biochemistry and Behavior · 2004 · 215 citations

, , +11

The overwhelming use of rat models in nerve regeneration research may compromise designs of nerve guidance conduits for humans

Hilton M. Kaplan, Prakhar Mishra, Joachim Kohn · Journal of Materials Science Materials in Medicine · 2015 · 156 citations · Full text

, , +17

Structure-guided inhibitor design for human FAAH by interspecies active site conversion

Mauro Mileni, Douglas S. Johnson, Zhigang Wang et al. · Proceedings of the National Academy of Sciences · 2008 · 152 citations · Full text

, , +15

Chitosan as a nasal delivery system: evaluation of insulin absorption enhancement and effect on nasal membrane integrity using rat models

Trudi Aspden, Lisbeth Illum, Øyvind Skaugrud · European Journal of Pharmaceutical Sciences · 1996 · 148 citations

, , +17

1–5 of 110

Authors

636

  1. LA
    Linda A. Parker

    University of Guelph, Canada

    3 publications · 193 citations

    3

    h-index

  2. LO
    Laure‐Hélène Ouisse

    Inserm, France

    3 publications · 148 citations

    3

    h-index

  3. IA
    Ignacio Anegón

    Inserm, France

    3 publications · 148 citations

    3

    h-index

  4. SR
    Séverine Remy

    Inserm, France

    2 publications · 60 citations

    2

    h-index

  5. SM
    Séverine Ménoret

    Inserm, France

    2 publications · 120 citations

    2

    h-index

1–5 of 636

Institutions

288

  1. Inserm

    Paris, France

    5 h-index

    26 publications

    957 citations

  2. Medical College of Wisconsin

    Milwaukee, United States

    4 h-index

    11 publications

    551 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    26 publications

    980 citations

  4. Institut de Transplantation Urologie en Nephrologie

    Nantes, France

    3 h-index

    22 publications

    896 citations

  5. Sorbonne Université

    Paris, France

    3 h-index

    9 publications

    377 citations

  6. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    4 publications

    102 citations

  7. Nantes Université

    Nantes, France

    2 h-index

    18 publications

    544 citations

  8. Heidelberg University

    Heidelberg, Germany

    2 h-index

    3 publications

    100 citations

1–8 of 288

Venues

  1. Methods in molecular biology

    Book series · 5 publications · 188 citations

    5

    h-index

  2. PubMed

    Repository · 4 publications · 115 citations

    4

    h-index

  3. International Journal of Pharmaceutics

    2 publications · 137 citations

    2

    h-index

  4. Scientific Reports

    2 publications · 61 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 194 citations

    2

    h-index

1–5